ID A0A1U8NJN1_GOSHI Unreviewed; 397 AA.
AC A0A1U8NJN1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=26S proteasome regulatory subunit RPN10 {ECO:0000256|ARBA:ARBA00044341};
GN Name=LOC107949106 {ECO:0000313|RefSeq:XP_016739312.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016739312.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016739312.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016739312.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the proteasome subunit S5A family.
CC {ECO:0000256|ARBA:ARBA00005574}.
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DR RefSeq; XP_016739312.1; XM_016883823.1.
DR AlphaFoldDB; A0A1U8NJN1; -.
DR STRING; 3635.A0A1U8NJN1; -.
DR PaxDb; 3635-A0A1U8NJN1; -.
DR GeneID; 107949106; -.
DR KEGG; ghi:107949106; -.
DR OrthoDB; 169547at2759; -.
DR Proteomes; UP000189702; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IBA:GO_Central.
DR GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd22297; PSMD4_RAZUL; 1.
DR CDD; cd01452; VWA_26S_proteasome_subunit; 1.
DR Gene3D; 1.10.287.3990; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR049590; PSMD4_RAZUL-like.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10223; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR PANTHER; PTHR10223:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR Pfam; PF02809; UIM; 3.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00726; UIM; 3.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50330; UIM; 2.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942,
KW ECO:0000313|RefSeq:XP_016739312.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 5..189
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 241..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 42174 MW; 7CD90F05C11D0CCC CRC64;
MVLEATMICI DNSEWMRNGD YSPSRFQAQA DAVSLICGAK TQSNPENTVG ILTMAGKGVR
VLATPTSDLG KILSCMHGLE MGGERNLAAG IQIAQLALKH RQNKNQQQRI IVFAGSPIKH
EKKALEMIGK KLKKNSVALD IVNFGEDEDG KPEKLEALLA SVNNNDTSHI VHVPAGQNAL
SDVLISTPVF TGDGEGGSGF AAAAAAAAAG GVSDFDFGVD PNIDPELALA LRVSMEEERA
RQEAAAKRAA EEATRQEKGE EAQPQSDSQN ATMNATEKAS DPMDEDDALL KQALALSMNI
PGSDSSAGDA QMSEATNDDQ EFALALQMSM QDGSKDSSAQ SDVSKVLGDQ YFMSSILSSL
PGVDPNDPKV KDLLASLPSQ SEPQEKKEED EQPKDDK
//
