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Database: UniProt
Entry: A0A1U8P3S5_GOSHI
LinkDB: A0A1U8P3S5_GOSHI
Original site: A0A1U8P3S5_GOSHI 
ID   A0A1U8P3S5_GOSHI        Unreviewed;       291 AA.
AC   A0A1U8P3S5;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   11-DEC-2019, entry version 10.
DE   SubName: Full=thymidylate kinase-like isoform X1 {ECO:0000313|RefSeq:XP_016744859.1};
GN   Name=LOC107953926 {ECO:0000313|RefSeq:XP_016744859.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016744859.1};
RN   [1] {ECO:0000313|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA   Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA   Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA   Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA   Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000313|RefSeq:XP_016744859.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_016744859.1};
RG   RefSeq;
RL   Submitted (APR-2017) to UniProtKB.
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DR   RefSeq; XP_016744859.1; XM_016889370.1.
DR   GeneID; 107953926; -.
DR   KEGG; ghi:107953926; -.
DR   KO; K00943; -.
DR   Proteomes; UP000189702; Genome assembly.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IBA:GO_Central.
DR   GO; GO:0004798; F:thymidylate kinase activity; IBA:GO_Central.
DR   GO; GO:0009041; F:uridylate kinase activity; IBA:GO_Central.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006227; P:dUDP biosynthetic process; IBA:GO_Central.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039430; Thymidylate_kin-like_dom.
DR   InterPro; IPR018095; Thymidylate_kin_CS.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   Pfam; PF02223; Thymidylate_kin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00041; DTMP_kinase; 1.
DR   PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|RefSeq:XP_016744859.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW   Transferase {ECO:0000313|RefSeq:XP_016744859.1}.
FT   DOMAIN          58..211
FT                   /note="Thymidylate_kin"
FT                   /evidence="ECO:0000259|Pfam:PF02223"
SQ   SEQUENCE   291 AA;  32932 MW;  53DC165BEE11CF65 CRC64;
     MAAVPLRNFD DFLVRRRSLN LRLNLSSEFP LRSIRMEISD NCTPLSANNE SRGALVVFEG
     LDRSGKTSQC GRLVSYLEGL GHSVELWRFP DRTTSVGQLI SAYLTNKSQL DDHTIHLLFS
     ANRWEKRSMM ETKLKAGTTL IVDRYSYSGV AFSTAKGLDF EWCKAPEIGL IAPDLVVYLD
     ITPEKAAERG GYGGERYEQL EFQRKVSQHY KLRKDSSWKG KQRGNLRVYM QGAPWIHLNL
     VKYFNTGIVV ALKIHLILDV LLLLMLLTTT NAGSPLSSKT DAGFKMNYVR C
//
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