ID A0A1U8P9R3_GOSHI Unreviewed; 693 AA.
AC A0A1U8P9R3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein VAC14 homolog {ECO:0000313|RefSeq:XP_016746994.1};
GN Name=LOC107955707 {ECO:0000313|RefSeq:XP_016746994.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016746994.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016746994.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016746994.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the VAC14 family.
CC {ECO:0000256|ARBA:ARBA00010225}.
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DR RefSeq; XP_016746994.1; XM_016891505.1.
DR AlphaFoldDB; A0A1U8P9R3; -.
DR STRING; 3635.A0A1U8P9R3; -.
DR PaxDb; 3635-A0A1U8P9R3; -.
DR GeneID; 107955707; -.
DR KEGG; ghi:107955707; -.
DR OrthoDB; 5481081at2759; -.
DR Proteomes; UP000189702; Chromosome 9.
DR GO; GO:0010008; C:endosome membrane; IBA:GO_Central.
DR GO; GO:0070772; C:PAS complex; IBA:GO_Central.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR026825; Vac14.
DR InterPro; IPR021841; VAC14_Fig4p-bd.
DR PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12755; Vac14_Fab1_bd; 1.
DR Pfam; PF11916; Vac14_Fig4_bd; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 92..127
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 429..608
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT REGION 668..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 77664 MW; ECC9C5132AE5D920 CRC64;
MADAFSVIPA SVLRNLSDKL YEKRKNAALE IEGIVKQLAS SGDHEKISAV IKLLATEFTD
SPQANHRKGG LIGLAAATVG LSSEAAQHLE QIVPPVLSSF SDQDSRVRYY ACEALYNIAK
VVRGDFIIFF NKIFDALCKL SADADANVQS AAHLLDRLVK DIVTESDQFS IEEFIPLLRE
RMNVLNPYVR QFLVGWITVL DSVPDIDMLG FLPDFLDGLF NMLSDSSREI RQQADSALSE
FLLEIKNSPS VDYGRMAEIL VQRAAALDEF TRLTAITWIN EFVKLGGDQL FPYYADILGA
ILPCISDKEE KIRVVARETN EALRSIEANP TENFDVGGIL SIAKRQLDSE WEATRIEALH
WISTLLTRHR AEVLCFLNDI FDTLLKALSD SSDEVVLLVL DIHACIAQDP LHFRQLVVFL
VHNFRIDHSL LERRGALIIR RLCVLLDAER VYRELSTILE GEADLDFACV MVQALNLILL
TSSELSELRE LLKQSLVNAA GKDLFVSLYA SWCHSPMAII SLCLLAQTYQ HACAVIQSLV
EEDINAKFLV QLDKLIRLLE TPVFAYLRLQ LLEPRQYIWL LKALYGLLML LPQQSSAFKV
LRRRLKTVPS YSFGGGNLKR AASGNPHSQI LHHSGSQITE DGDIDQDNGN LQSGINFASL
QQFKQMQQQH HMLAKSRAQS RNSSTSILKE GPK
//
