ID A0A1U8PAJ3_GOSHI Unreviewed; 1006 AA.
AC A0A1U8PAJ3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Kinesin-4-like {ECO:0000313|RefSeq:XP_016748170.1};
GN Name=LOC107957224 {ECO:0000313|RefSeq:XP_016748170.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016748170.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016748170.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016748170.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-14 subfamily.
CC {ECO:0000256|ARBA:ARBA00010899}.
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DR RefSeq; XP_016748170.1; XM_016892681.1.
DR STRING; 3635.A0A1U8PAJ3; -.
DR PaxDb; 3635-A0A1U8PAJ3; -.
DR OrthoDB; 54358at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0007017; P:microtubule-based process; IBA:GO_Central.
DR CDD; cd21203; CH_AtKIN14-like; 1.
DR CDD; cd01366; KISc_C_terminal; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972:SF12; KINESIN-LIKE PROTEIN KIN-14H; 1.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00033; CH; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 40..162
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 412..738
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 766..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..874
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 901..931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..1006
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 495..502
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1006 AA; 110768 MW; A565DD4A9F8C53BF CRC64;
MATETNLQVS VKSIFEDVLQ QQGARSCNIY LDSRKSDESS LRRYEAAGWL RRTVGVVGGK
DLPAEPSEEE FMHGLRSGII LCNVLNKVQP GSVPKVVEGA CDSVILSDGS AFSAYQYFEN
VRNFRVAIQE MGLPTFETSD LEQGGKSSRV VNCVLALKSY GEWKQSGRIG TWKYSANSKP
AGFGIAKSLS RKRSESLNSS FSEKSLDSFC SDQSDSIEAG SVSSFGILVR AALSDKKQEE
IPMIVESMIN KLSEXXESRL ASHKELTKIT AKAMEESATG HSLSQTASCD DKAEGVEVKA
SSAEEMVGDE SSSIASERKE LYDYKSDANE EPMQHVLKLH ALVERQRRDI QELKHCLCST
KTCMQVLQMT YQEDVFNLGK HLCSLANAAS GYQRVLEENR KLYNQVQDLK GNIRVYCRVR
PFKPGQSNTL SSVDHMDERT ITILTHSKNG KEARKAFTFN KVFGPSVSQA EVFSDMQPLV
RSVLDGYNVC IFAYGQTGSG KTHTMTGPKE LTEEGLGVNY RALSDLFHIS NQRKETISYD
ISVQMLEIYN EQVRDLLSAD GVNKRLEIRN SSQNGINVPD ANLVPVSLTS DVINLMSIGH
KNRSVCSTAL NDRSSRSHSC LTVHVQGRDL TSGNILRGSM HLVDLAGSER VDKSEVVGNR
LKEAQHINKS LSALGDVISS LASRSSHVPY RNSKLTQLLQ DSLGGQAKTL MFVHIAPEYE
ALGETISTLK FAERVATVEL GAAKVNKDSG EVKELKEQIA SLKAALARKE GDPENLPGSP
ERNRSKLGSS PSFLKWKSLS DLSCSTVNTE YESSSTSRRD SLESRETLVN PSHWQPLGSP
LSSSFTNEDD RDSEASGDWV DKVMVNKHDN MSTRPGKEVS NGQKLSDKFY QSYIPDPTKI
YPEHSLHKMT TNKKGNRDFD DDSDRESVTS DCSESDSVSS SIPKITSSPN MFASKQKKPQ
SKTTAKSTEI RSSIPSLIPS PSSMRKSPSG VNPNLQKGKR KTGLSK
//
