ID A0A1U8PBB8_GOSHI Unreviewed; 380 AA.
AC A0A1U8PBB8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=5'-3' exonuclease-like {ECO:0000313|RefSeq:XP_016748482.1};
GN Name=LOC107957481 {ECO:0000313|RefSeq:XP_016748482.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016748482.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016748482.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016748482.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016748482.1; XM_016892993.1.
DR AlphaFoldDB; A0A1U8PBB8; -.
DR STRING; 3635.A0A1U8PBB8; -.
DR PaxDb; 3635-A0A1U8PBB8; -.
DR GeneID; 107957481; -.
DR KEGG; ghi:107957481; -.
DR OrthoDB; 394414at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF4; 5'-3' EXONUCLEASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|RefSeq:XP_016748482.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_016748482.1};
KW Nuclease {ECO:0000313|RefSeq:XP_016748482.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 89..354
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 380 AA; 43008 MW; ED30FF954A462941 CRC64;
MVEVTVAAWI SHAPCLTPNS FHSISNGKSR NKTTKVVPTS TKAWKIRTAV AAASCSSSVF
GSFNQTVGGQ VLREGECLEK YKKEGKGKKR VFFLDVNPLC YAGNKPSLQS FGHWVSLFFS
QVCLTDPVIA VFDGNNCNEL RRRLLPSYKA HRRKFFPQST ISKKYVRGQV GRSQQLIMDV
LRKCNVPVLK VEGNEADDVV ATLVEQVLER GYHVVIASPD KDFKQLISEN VQIVMPLVEL
KRWSFYTLKH YMAQYNCDPQ SDLSLRCIMG DEVDGVPGIQ HLVPGFGRRT ALKLLKKHGS
LENLLNAASV RTVGRQYAQE ALTKYADYLR RNYEVLALRR DVDVHLQEEW LLERDTSNDA
NVLSNFFRLL EETNKSTRES
//
