ID A0A1U8PC64_GOSHI Unreviewed; 568 AA.
AC A0A1U8PC64;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=tRNA modification GTPase MnmE-like {ECO:0000313|RefSeq:XP_016748776.1};
GN Name=LOC107957725 {ECO:0000313|RefSeq:XP_016748776.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016748776.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016748776.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016748776.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family. {ECO:0000256|ARBA:ARBA00011043,
CC ECO:0000256|RuleBase:RU003313}.
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DR RefSeq; XP_016748776.1; XM_016893287.1.
DR AlphaFoldDB; A0A1U8PC64; -.
DR STRING; 3635.A0A1U8PC64; -.
DR PaxDb; 3635-A0A1U8PC64; -.
DR OrthoDB; 5478664at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IBA:GO_Central.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00450; mnmE_trmE_thdF; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51709; G_TRME; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003313};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003313};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694,
KW ECO:0000256|RuleBase:RU003313}.
FT DOMAIN 323..489
FT /note="TrmE-type G"
FT /evidence="ECO:0000259|PROSITE:PS51709"
SQ SEQUENCE 568 AA; 61370 MW; EFE9E2C67D91E228 CRC64;
MIISENSHTA TMALLPSFRT IITRFYRPTK PPPQLIFSSL LFPKKLSSLF PLPPKPQPLK
PLASTRQETS FVSNRDERLV GLGSVNDGGS IETQSSTSTI AAIVTSLGGP PAAVGIVRLS
GPNAVDIAGR VFSPAKKKKR FDSGSGSWKP KSHIVEYGVV LDSQGNVVDE VLAVPMLAPK
SYTREDVVEL QCHGSEVCLR RVLKACLEAG ARLAEPGEFT LRAFLNGRLD LSQAENVGKL
ISAKSVAAAD AALAGIQGGF STLVRSLREQ CIELLTEIEA RLDFEDEMPP LDVNVIMDRM
HAMSQDVEHA LETANYDKLL QSGLQIAIVG RPNVGKSSLL NAWSKSERAI VTEIAGTARD
VVEASVSVAG VAVTLLDTAG IRETDDIVEK IGVERSEAVA MGADVIIMTV SAIDGWTLED
TKLVERIRSN MGSASIPMIL VINKIDCASS ACSDWVNREA KLFSKHVFTC AITGQGIHDL
EKSILEIVGL DKIPAGGRRW TVNQRQCEQL MRAKEALVRL KSTIEEELPL DFWTIDLKEA
ALALGQISGD DISEEILSNI FGKFCIGK
//
