ID A0A1U8PFV6_GOSHI Unreviewed; 1004 AA.
AC A0A1U8PFV6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc protease PQQL-like {ECO:0000313|RefSeq:XP_016750111.1};
GN Name=LOC107958766 {ECO:0000313|RefSeq:XP_016750111.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016750111.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016750111.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016750111.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016750111.1; XM_016894622.1.
DR AlphaFoldDB; A0A1U8PFV6; -.
DR STRING; 3635.A0A1U8PFV6; -.
DR PaxDb; 3635-A0A1U8PFV6; -.
DR GeneID; 107958766; -.
DR KEGG; ghi:107958766; -.
DR OrthoDB; 448605at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 2.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670,
KW ECO:0000313|RefSeq:XP_016750111.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 57..172
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 210..390
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT DOMAIN 697..879
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 1004 AA; 112847 MW; D2FDCFB9DEE9ACA2 CRC64;
MDLLPIDNSQ IAKKHGFRSL KLVNVDLDQE FQHQPFGVDY GRLDNGLTYY VRSNPKPRLR
AALALAVKVG SVLEEEGERG VAHIVEHLAF SATKKYTNHD IVKFLESIGA EFGACQNAVT
SADDTVYELF VPIDRPELLS QAISVLAEFS SEIRVSKDDL EKERGAVMEE YRGNRNASGR
MQDAHWALMM EGSKYAERLP IGLEKVIRTV SSETVKQFYK KWYHLHNMAV IAVGDFPDTE
SVVELIRTHF EGKNSGPDPP IIPSFPVPSH EDPRFSCFVE SEAAGSAVMI SYKMPADELN
TVKDYRDMLV ESMFLHALNQ RFFKLSRRKD PPYFSCSAAS DALVSPLKAY IMSSTCKEKG
TLQALESMLI EVARVRLHGF SEREVSVVRA LLMSEIESAY LERDQMQSTS LRDEYIQHFI
HNEPVIGIEY EAQLQKSILP YISASEVSKY AEKLQTSCSC VLKTIEPQAS ATVDDLKKVV
LKINNLEKEG SIAPWDDEYI PEEIVNIKPD PGYIVEQIEY SNIGATELTL SNGMRVCYKC
TDFFDDQVLF TGFSYGGLSE LPESEYFSCS MGSTIAGEIG VFGHKPSVLM EMLAGKRVEV
GTKLGAYMRT FSGDCSPSDL ETALQLVYQL FTTNVIPGEE EVKIVMQMAE EAVRAQERDP
YTAFANRVKE INYGNSYFFR PIRLSDLRKV DPVKACEYFN RCFKDPSTFT VVITGNIDPT
IALPLILQYL GGIPKSPEAI FHYNRDDLKG LPFKFPKTVI RDVVRSPMVE AQCSVQLCFP
VVLKNGTMVE EIHCVGFLSK LIETKIVQVL RFKHGQIYSA CVSVFLGGNK PSRTGDVRGD
VSINFSCDPE ISSKLVDLAL DEVVHLQEEG PTDQDVSTVL EIEQRAHENG LQENYYWLER
ILRSYQSRIY SGDVGTSFKI QDEGRSRVRE TLTPSTAQSA LRRILPYPCK KQYTVVILMP
QASRFKLLRS LFKQNAPSRD AKILAAIAGG TVLAACLWRY SRKS
//
