ID A0A1U8PM43_GOSHI Unreviewed; 936 AA.
AC A0A1U8PM43;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Respiratory burst oxidase homolog protein D-like {ECO:0000313|RefSeq:XP_016752252.1};
GN Name=LOC107960417 {ECO:0000313|RefSeq:XP_016752252.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016752252.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016752252.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016752252.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the RBOH (TC 5.B.1.3) family.
CC {ECO:0000256|ARBA:ARBA00007975}.
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DR RefSeq; XP_016752252.1; XM_016896763.1.
DR AlphaFoldDB; A0A1U8PM43; -.
DR STRING; 3635.A0A1U8PM43; -.
DR PaxDb; 3635-A0A1U8PM43; -.
DR GeneID; 107960417; -.
DR KEGG; ghi:107960417; -.
DR OrthoDB; 367877at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016174; F:NAD(P)H oxidase H2O2-forming activity; IBA:GO_Central.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR000778; Cyt_b245_heavy_chain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR013623; NADPH_Ox.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR PANTHER; PTHR11972:SF152; RESPIRATORY BURST OXIDASE HOMOLOG PROTEIN D; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR Pfam; PF08414; NADPH_Ox; 1.
DR PRINTS; PR00466; GP91PHOX.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SFLD; SFLDG01169; NADPH_oxidase_subgroup_(NOX); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 259..294
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 613..737
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 105726 MW; 2F42B4FAD87FD1EC CRC64;
MKNEDWRGGY SETNSDTERI ASERATFSGP LGVGVGIVSN KRASKKSATF NLPPEITMSK
ANSARTVASF DSSAVAAAGD DDYVEITLDI LDDSVAVHSV QGADGGYEDP ELSLLAKRTL
ENKSASFRSY LFRNTSARIK QFSQELKRAV SRRSSNAGRR FDRNKSAAAH ALKGLKFITT
KTGASGNGWS SVEKRFDDLT APTNGLLHRS QFAECIGMNQ SKEFAGALFQ ALARRHNVTG
DSINKIQLKQ FWDQISDESF DSRLQTFFDM VDKDADGRIT EAEVKEIISL SASANRLSNI
QKQAEEYAAL IMEELDPDNA GYIMIHNLET LLLQAPNQSV RVGDSRILSQ MLSQKLKPTQ
ENNPLKRWYH KTKYFIIDNW QRIWVMMLWL GIMGSLFAYK FVQYRNKAVF DVMGYCVCVA
KGSAETLKFN MALILLPVCR NTITWLRNKT KLGAVVPFDD NLNFHKVIAV GISIGVALHG
IAHLACDFPR LLHATEEEYE PMEPFFGEEQ PPNYWWFLKG VEGITGIIMV VLMAIAFTLA
TPWFRRNKLN LPKFLKKLTG FNAFWYSHHL FVIVYSLLIV HGIYLYLTKK WYQKTTWMYL
AVPITLYACE RLIRAFRSSI KAVKILKVAV YPGNVLSLHM SKPQGFKYKS GQFMFVNCSA
VSSFEWHPFS ITSAPGDDYL SVHIRTLGDW TRQLKTVFSE VCQPPPAGKS GLLRAEGTNT
SFPKILIDGP YGAPAQDYKK YDVVLLVGLG IGATPMISIV KDIINNMKME EMEEDSFPGS
GLENGNYNKN KNKNNKGFKT RKAYFYWVTR EQGSFEWFKG IMNEVAEMDE QWVIELHNYC
TSVYEEGDAR SALITMLQSL HHAKNGVDVV SGTRVKSHFA KPNWRQVYKN IVLHHQGARI
GVFYCGAPAL TKELRQLALD FSHKTGTKFD FHKENF
//
