ID A0A1U8PPC6_GOSHI Unreviewed; 411 AA.
AC A0A1U8PPC6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Probable serine incorporator isoform X2 {ECO:0000313|RefSeq:XP_016752079.1};
GN Name=LOC107960278 {ECO:0000313|RefSeq:XP_016752079.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016752079.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016752079.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016752079.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TDE1 family.
CC {ECO:0000256|ARBA:ARBA00006665}.
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DR RefSeq; XP_016752079.1; XM_016896590.1.
DR AlphaFoldDB; A0A1U8PPC6; -.
DR GeneID; 107960278; -.
DR KEGG; ghi:107960278; -.
DR OMA; NYEMMTS; -.
DR OrthoDB; 296357at2759; -.
DR Proteomes; UP000189702; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005016; TDE1/TMS.
DR PANTHER; PTHR10383:SF54; SERINC-DOMAIN CONTAINING SERINE AND SPHINGOLIPID BIOSYNTHESIS PROTEIN; 1.
DR PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR Pfam; PF03348; Serinc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..411
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010529578"
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 411 AA; 45577 MW; E49FCC0EB61B1B21 CRC64;
MWAASCLASC CAACACDACR TVVSGISRRS ARIAYCGLFA LSLVVSWILR EVAAPLMEKL
PWINHFHKTP DREWFETDAV LRVSLGNFLF FTILSVSMVG VKNQRDPRDA VHHGGWMMKI
ICWFILVILM FFVPNEIISF YESASKFGAG LFLLVQVVLL LDFVHGWNDK WVGYDEQFWY
VALLVVSLVC YLATFGFSGL LFHWFTPSGQ DCGLNTFFIV MTLTLVLLFA IVALHPAVGG
SILPASVISL YCMYLCYSGL ASEPRDYECN GLHKHSKAIS TGTLTLGLLT TVLSVVYSAV
RAGSSTTLLS PPSSPRAGKP LLPMDKADEH EEKEKNKPVS YSYAFFHIIF SLASMYSAML
LTGWSTSVGE SGKLVDVGWP SVWVRIITGW ATAGLYVWSL VAPILFPERE F
//
