ID A0A1U8PX96_GOSHI Unreviewed; 312 AA.
AC A0A1U8PX96;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=DNA repair helicase XPB1-like {ECO:0000313|RefSeq:XP_016755771.1};
GN Name=LOC107963805 {ECO:0000313|RefSeq:XP_016755771.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016755771.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016755771.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016755771.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR RefSeq; XP_016755771.1; XM_016900282.1.
DR AlphaFoldDB; A0A1U8PX96; -.
DR STRING; 3635.A0A1U8PX96; -.
DR PaxDb; 3635-A0A1U8PX96; -.
DR Proteomes; UP000189702; Chromosome 12.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR InterPro; IPR001161; XPB/Ssl2.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR NCBIfam; TIGR00603; rad25; 1.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|RefSeq:XP_016755771.1};
KW Helicase {ECO:0000313|RefSeq:XP_016755771.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_016755771.1};
KW Nucleotide-binding {ECO:0000313|RefSeq:XP_016755771.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702}.
FT DOMAIN 66..190
FT /note="Helicase XPB/Ssl2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13625"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 35274 MW; EFF703BC430775BD CRC64;
MGHGERGRPN KKFKFAKDDH RGSAMEDDYS FYPDEADDEP RDGENEGKKR DFTKLELKLD
HGNRPLWACA DGRIFLETFS PLYKQAYDFL IAIAEPVCRP ESMHEYNLTP HSLYAAVSVG
LETETIISVL NKLSKTKLPK EMIDFIHAST ANYGKVKLVL KKNRYFIESP FPEVLKKLLQ
DEVIGRARLV SENVQGNDGF TISKTAGEIE SGHSGLLMES ELAAAAEEKE THAFEIDPAQ
VENVKQRCLP NALNYPMLEE YGFRNDSVNP DLDMELKPHA QPRPYQEKSL SKMFGNGEII
NTIICSTNCY CA
//
