ID A0A1U8PXY3_GOSHI Unreviewed; 220 AA.
AC A0A1U8PXY3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RNA-directed DNA polymerase homolog {ECO:0000313|RefSeq:XP_016755228.1};
GN Name=LOC107963161 {ECO:0000313|RefSeq:XP_016755228.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016755228.1};
RN [1] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [2] {ECO:0000313|RefSeq:XP_016755228.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016755228.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016755228.1; XM_016899739.1.
DR AlphaFoldDB; A0A1U8PXY3; -.
DR STRING; 3635.A0A1U8PXY3; -.
DR PaxDb; 3635-A0A1U8PXY3; -.
DR Proteomes; UP000189702; Chromosome 11.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR35046:SF9; CCHC-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR35046; ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|RefSeq:XP_016755228.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW RNA-directed DNA polymerase {ECO:0000313|RefSeq:XP_016755228.1};
KW Transferase {ECO:0000313|RefSeq:XP_016755228.1}.
FT DOMAIN 1..155
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 220 AA; 26263 MW; 4B1CD25EA9F489C0 CRC64;
MWRMCVDCRA VNQITIKYLH SIPQLDNKLD ELCGATIFSK IDLKSGYHQI RVREGDEWKT
TFKTKLGLYE WLVMPFGLTN EPSTFMRLMN HVLRSFIGKF CVVYFDDILI YSKTLQDYVE
HLRDVMHTLR EEKLFRNMEK CVFCTDKLTF LSYIVSSQGV EVDPKKEKRP VVYFSEKLSR
TMLNYPVYDK EMYALIRALE TWQHYLLPKE FTIHTDHEAL
//
