ID A0A1U8PZP5_NELNU Unreviewed; 733 AA.
AC A0A1U8PZP5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Formin-like protein 5 {ECO:0000313|RefSeq:XP_019052007.1};
GN Name=LOC104590175 {ECO:0000313|RefSeq:XP_019052007.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_019052007.1};
RN [1] {ECO:0000313|RefSeq:XP_019052007.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
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DR RefSeq; XP_019052007.1; XM_019196462.1.
DR AlphaFoldDB; A0A1U8PZP5; -.
DR STRING; 4432.A0A1U8PZP5; -.
DR GeneID; 104590175; -.
DR KEGG; nnu:104590175; -.
DR eggNOG; KOG1922; Eukaryota.
DR InParanoid; A0A1U8PZP5; -.
DR OrthoDB; 623207at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF385; FORMIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..733
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010521277"
FT TRANSMEM 244..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 521..733
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 173..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..507
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 79722 MW; 16E8E3CF46BE4270 CRC64;
MDARSASSVI TFVILFFALA TGSSEGTRRA GKFYWANGIA VASSPEIEID EDMAEELWIK
CRLDLVQMKE SDKNIDLNFP EQIAIGSNGI NSEVQSLENG NLQKAISALP SQTIEILLDC
LRKKDHFYIS GEEGGSKNWY TKYMEFLFGW PEYSRRFLGG VLLQNVVSPA QAPAVEPPTY
GPRPSSAPAP ATSYIHPPVE APKLPFFPRD FSDSSPQPST SHSSVDPIVA PGTPSRKHNN
RKPVVIAVVV TAVGTLVFAS MLFFFYLKCY RSRTNTGSGD GQKDDRPLLS LGLSDYSVDY
QLSGSSQRYS THGSSINKDK YGTQLFNTNI NQNGRASSLN SNLSVKPDVH NSSPSEAPLS
GRITGAAKTP VEPSTSSSNI HATVPSLPLK LPPGRARPAP HLPPIPSELQ PSPPPIVPSN
PPPPPSGPPR PPPSIPSGLR PPPPVPSGPP PPPPIPSGPR PQPPVRSGLR PPSPISSGPP
PPPPPIPSAR PRPPLPPGPP PPKNVFFPTP GNAVNEGTSL KAHAEAPKAK LKPFFWDKVL
ANPDHSMVWH QISSGSFQFN EEMIETLFGY AAADKNKNER KKESLSQDPS SQYVQLIDSK
KSQNLSILLR ALNVTTEEVC DALQEGNELP IELLEALLKM APTAEEELKL RLFNGELSQL
GPAERFLKVL VDIPFSFKRF DCLLFMGSLQ EEASVIKESL ATLEVRPSMF ELKIFLIRDP
TLLHQQMVSE QGY
//
