ID A0A1U8Q6B1_NELNU Unreviewed; 362 AA.
AC A0A1U8Q6B1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Monofunctional riboflavin biosynthesis protein RIBA 3, chloroplastic isoform X3 {ECO:0000313|RefSeq:XP_019053600.1};
GN Name=LOC104599270 {ECO:0000313|RefSeq:XP_019053600.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_019053600.1};
RN [1] {ECO:0000313|RefSeq:XP_019053600.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005104}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the GTP
CC cyclohydrolase II family. {ECO:0000256|ARBA:ARBA00008976}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the DHBP synthase
CC family. {ECO:0000256|ARBA:ARBA00005520}.
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DR RefSeq; XP_019053600.1; XM_019198055.1.
DR AlphaFoldDB; A0A1U8Q6B1; -.
DR GeneID; 104599270; -.
DR OrthoDB; 5489599at2759; -.
DR UniPathway; UPA00275; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0008686; F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.870.10; DHBP synthase; 1.
DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR InterPro; IPR017945; DHBP_synth_RibB-like_a/b_dom.
DR InterPro; IPR000422; DHBP_synthase_RibB.
DR InterPro; IPR032677; GTP_cyclohydro_II.
DR InterPro; IPR036144; RibA-like_sf.
DR NCBIfam; TIGR00506; ribB; 1.
DR PANTHER; PTHR21327; GTP CYCLOHYDROLASE II-RELATED; 1.
DR PANTHER; PTHR21327:SF29; GTP CYCLOHYDROLASE-2; 1.
DR Pfam; PF00926; DHBP_synthase; 1.
DR Pfam; PF00925; GTP_cyclohydro2; 1.
DR SUPFAM; SSF142695; RibA-like; 1.
DR SUPFAM; SSF55821; YrdC/RibB; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Riboflavin biosynthesis {ECO:0000256|ARBA:ARBA00022619}.
FT DOMAIN 323..355
FT /note="GTP cyclohydrolase II"
FT /evidence="ECO:0000259|Pfam:PF00925"
SQ SEQUENCE 362 AA; 38980 MW; C9857B893726117E CRC64;
MDCLWVQHLL YPQIFLSSRF HRSFRTSLYP GLRLSRTTGF FSSGGCCQVG ATRIGGGELF
GDGSPLENEN GALFGAVDES SMATFGTVNA EITPETVDFF VSDAEGDPDR PSEGFSAIDK
ALDALRQGKF VIAVDDENGD VEGNLIMAAS LASTQAMAFM VKHGSGIVSV GMKEDDLERL
KLPLMSPESR DEDSSAPSFT VTVDAKAGVT TGVSASDRAK TVLALSSPDS NPEDFTRPGH
VFPLKYRTGG VLRRVGHTEA SVDLVTLAGL RPVSVISAII NADDGSMASL PYLRKLATEH
GLPIVLITDL IRYRRKREKL VERSAVSRLP TKWGPFQAYC YRSKLDGTEH IAIVKINGDP
AS
//
