ID A0A1U8QBT1_NELNU Unreviewed; 1187 AA.
AC A0A1U8QBT1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DNA polymerase I A, chloroplastic/mitochondrial-like isoform X2 {ECO:0000313|RefSeq:XP_019055571.1};
GN Name=LOC104610895 {ECO:0000313|RefSeq:XP_019055571.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_019055571.1};
RN [1] {ECO:0000313|RefSeq:XP_019055571.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_019055571.1; XM_019200026.1.
DR AlphaFoldDB; A0A1U8QBT1; -.
DR GeneID; 104610895; -.
DR OrthoDB; 208079at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd08640; DNA_pol_A_plastid_like; 1.
DR CDD; cd06139; DNA_polA_I_Ecoli_like_exo; 1.
DR Gene3D; 3.30.70.370; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 2.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189703}.
FT DOMAIN 948..1147
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 828..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..856
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1187 AA; 134095 MW; 720AB84107B09CBF CRC64;
MAMGVSTQSG PLKPCSSSPF WSSPSCRRSA SMTSSPHACS GSSKSFQRKE FHSVQYENVC
NCNFTGSFIQ FKRGLSNSTG SVITKDGACE RKRCCPYPYY CWRLEVRTQM SHSPTSSARM
FPYYSNQIDS ERKLQAVRLV NMRNSEEEEK QTPRHHGPPL EDVDVSPPCQ SSDYKTSNYR
ATENMISRNS SLDIDSWLEE RRRLREIRSE VRRSIELGTF NDGGSCGNFD SHPDPFHGLR
FDNINGKKSL QCSFNQENMG FDFDNVQACK PPYKPSDRET CTVKCQCRVT MKSSSASHVT
TQHESRSCNN VAINNACNLT VNKLAQVSLY STQIARDQAQ LSESLPLKPF EENEGQLNKL
DGLGMGTNDI TERIPSNSRY STNAEESVET YTISINPRGE YVFHQPEYHE MLSHIYKKVL
VVDNIAVAKE IVRMLTTRYK DLVHACDTEV AKIDAKQETP VDHGELICFS IYSGPEVDFG
NGKSCIWVDV LDGGGRDILM EFAPFFEDPS IRKVWHNYSF DSHVIENYGL KISGFHADTM
HMARLWDSSR RKEGGYSLEA LTMDPKVMSE VQQCTKGEPI KKKWCTEGEL IGKISMKTIF
GKKKIKKDGS EGKVVTVPPV EELQREERIP WIFYSTLDSI STLKLFESLK IKLKNMEWVL
DGVKRGTMYD FYEEYWRPFG ELLVKMETEG MLVDRAYLAE MEKVATEEQQ VAAKRFCKWA
SRYCSDAIYM NVGSDAQLRQ LFFGGTVNRK NPDESLPLER TFRVLNVDKV TQKGKKAPPK
YRNITLCKLG NEMQTEMYTA TGWPSVSMGA LKNLSGKVSA EYDFTDYSSQ SSESNDILPE
QTVNEVEKRK GTSVSEEETD ISAYGTAYTA FGGGKEGREA CHAIAALCEV CSIDSLVSNF
ILPLQGSHIL GKNGRVHCSL NINTETGRLS ARRPNLQNQP ALEKDRYKIR QAFIAAPGNS
LIVADYGQLE LRILAHLANC KSMLDAFKAG GDFHSRTAMN MYPHIRKAVE QKQVLLEWHP
QTGEVKPPVP LLKDAFASER RKAKMLNFSI AYGKTPVGLA RDWKVSVTEA KETLKLWYKD
RQEVLHWQEE RKQEAAKGCV YTLLGRSRRF PSMDHASNAQ CGHIERAAIN TPVQVHDEVI
LEGPNESAEE ARAIVVKCMS KPFYGTNFLK VDLSVDAKCA RNWYAAK
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