ID A0A1U9JI34_9NEIS Unreviewed; 965 AA.
AC A0A1U9JI34;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BXU06_00665 {ECO:0000313|EMBL:AQR63741.1};
OS Aquaspirillum sp. LM1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Aquaspirillaceae; Aquaspirillum.
OX NCBI_TaxID=1938604 {ECO:0000313|EMBL:AQR63741.1, ECO:0000313|Proteomes:UP000188659};
RN [1] {ECO:0000313|EMBL:AQR63741.1, ECO:0000313|Proteomes:UP000188659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LM1 {ECO:0000313|EMBL:AQR63741.1,
RC ECO:0000313|Proteomes:UP000188659};
RA Hentchel K., Vargas G., Fiebig A., Chen S.L., Coleman M., Crosson S.;
RT "Genome sequences of bacteria isolated from the littoral zone of southern
RT Lake Michigan.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP019509; AQR63741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U9JI34; -.
DR STRING; 1938604.BXU06_00665; -.
DR KEGG; aql:BXU06_00665; -.
DR Proteomes; UP000188659; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR004010; Double_Cache_2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033480; sCache_2.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF08269; dCache_2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM01049; Cache_2; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000188659};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 399..454
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 472..524
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 556..694
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 703..957
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 965 AA; 108644 MW; F2A914E7D36954D4 CRC64;
MEKDLTAQSL ARLQLWAMVG ISLLVALVLG LYFFLAQRAD FDSTLSAVKA RALQEQQNLL
TKQIEAIRHD LDYRRSSTES ILRREIQQRV DHAYSIADTL YQQNQGRLNP QQIRALIVEA
LRPLRFFEGR GYYFIDTLDG MCVLLPTAPQ LEGTSFWDNR DPTGHYIMRG LVDATRNPAQ
AGFSRYHWYP PQQKTMQEKI AYVRVFAPLG WVIGAGEYVY NVEQDLQRAA LSQLRTLRFG
RDGYVSVFDA QFRVLVSPAR PDSEGKTVDA FSGLEKRSVE TIIAQARRGD GLVRYQWYRP
GSTLAVDKLS YVARYAPWGW TLVTGMYLDD LDSVMAAERQ AMEARTRQRL MIGGMITLGV
LTVALLFSWM FSVRMRGLVR RYQARLEQKN HELEDNARRL QLSAAVFESG CEAIMISDAD
NRIIAVNQPF TRITGYQPED VIGQAPQLFA SSHPGGDFYA ELGQALLSHG QWDGEVWSRR
KDGSVFPEWL RVATVKNSAG QIEYHIATFS DISERKNAEE QIRHLAFYDP LTGLPNRRLL
LDRLQQALLH SERVGCHAAV LFIDLDNFKS LNDTKGHDVG DLLLIEVASR LKHSVRQTDT
VARLGGDEFV VMLEDLPGDF AQAVSDTEKL AHSLIAAIEQ PFGLAQYQHH CSCSIGISVF
YGQRESVDEL LKHADTAMYQ AKAAGRNTAR FFVPSMQAAL EARLQLEAEL RHGIFHDQLR
LFYQVQIGVD QHASGAEALV RWQHPQRGLV SPGEFIGLAE ETGLIVPLGL WVLEQVCQQL
ARWAAAPLTE PLQIAVNVSA RQFHQAGFVD DVCQLLQRYQ VNPARLKLEL TESLLLDNVA
DSINTMHALR ALGIRFSMDD FGTGYSSLTY IKRLPIDQLK IDQSFIRDLA VDHDDEVIVR
AIIAMAHSLK LDVIAEGVET EAQRAFLEQH GCHAFQGYLF GRPMPVAQLE ALLAQWGKPS
GKSSL
//
