ID A0A1U9K8N7_9BACL Unreviewed; 585 AA.
AC A0A1U9K8N7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN ORFNames=B0W44_12165 {ECO:0000313|EMBL:AQS56402.1};
OS Novibacillus thermophilus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Novibacillus.
OX NCBI_TaxID=1471761 {ECO:0000313|EMBL:AQS56402.1, ECO:0000313|Proteomes:UP000188603};
RN [1] {ECO:0000313|EMBL:AQS56402.1, ECO:0000313|Proteomes:UP000188603}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG-1 {ECO:0000313|EMBL:AQS56402.1,
RC ECO:0000313|Proteomes:UP000188603};
RX PubMed=25951858; DOI=10.1099/ijs.0.000306;
RA Yang G., Chen J., Zhou S.;
RT "Novibacillus thermophilus gen. nov., sp. nov., a Gram-staining-negative
RT and moderately thermophilic member of the family Thermoactinomycetaceae.";
RL Int. J. Syst. Evol. Microbiol. 65:2591-2597(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP019699; AQS56402.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U9K8N7; -.
DR STRING; 1471761.B0W44_12165; -.
DR KEGG; ntr:B0W44_12165; -.
DR OrthoDB; 9776552at2; -.
DR Proteomes; UP000188603; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000188603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..367
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 585 AA; 67666 MW; 826BDF9B8E22C4DE CRC64;
MRRHWGLRRK FVILFLVFIT LPTVLFGFRV YYQSSVSLNK QAEKDLVSKL EKNEQILLSI
IKNVESMTSY MIYDQDFRTF FTTAEEEMHR LEYKNAVKGI NGYFTFQLMS NEYISSVYLE
GKDGHSLRFG EPIKGNEGRL DRVAEEGEGA PVWSHAYRVT SDWDGEKYLI SVSRIVNDLN
RINDPIGKVR IRLDSSKLFK HLEANASTQT GHYFVVTMQG DVVIHHNPSY VGKRYPDPKL
TDWAINGELS SYNYETDSGN YLVVKKRLEG TNWISVAVVD EGELVKELHN VQGSVRNMVI
VLFLLGMAGF AFFYQSNVKR IIALTTQIKQ VENANFAASV DVNSSDEIGK LGMQFNKMVQ
NIKRYIDSEY KLKIKQKESE LKALQSQMDP HFLYNTLDMI RWTARLENAM ETGQLIEQLS
KVFRMNVKND NMWVLLEDEL AYIQAYLELQ KSRMGDRLDF SIVMDDRVKG HLVMKQMLQP
LVENSIQHGF KQLPRQGMIY IRCYQANAQL WIDVIDNGWG FQTEDKTNDR HTGYALNNLK
DRLNIAFGEK YGLVPLDTNE GAAYRLVLPL LNEEKLKEIQ KETGE
//
