ID A0A1U9KR75_9PROT Unreviewed; 369 AA.
AC A0A1U9KR75;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN ORFNames=A0U93_10835 {ECO:0000313|EMBL:AQS88354.1}, NCH01_10210
GN {ECO:0000313|EMBL:GEN14590.1};
OS Neoasaia chiangmaiensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Neoasaia.
OX NCBI_TaxID=320497 {ECO:0000313|EMBL:AQS88354.1, ECO:0000313|Proteomes:UP000188604};
RN [1] {ECO:0000313|EMBL:AQS88354.1, ECO:0000313|Proteomes:UP000188604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101099 {ECO:0000313|EMBL:AQS88354.1,
RC ECO:0000313|Proteomes:UP000188604};
RA Brandt J., Jakob F., Vogel R.F.;
RT "Acetic acid bacteria sequencing.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GEN14590.1, ECO:0000313|Proteomes:UP000321095}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101099 {ECO:0000313|EMBL:GEN14590.1,
RC ECO:0000313|Proteomes:UP000321095};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Neoasaia chiangmaiensis NBRC 101099.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
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DR EMBL; CP014691; AQS88354.1; -; Genomic_DNA.
DR EMBL; BJXS01000003; GEN14590.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U9KR75; -.
DR STRING; 320497.A0U93_10835; -.
DR KEGG; nch:A0U93_10835; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000188604; Chromosome.
DR Proteomes; UP000321095; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 1.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:AQS88354.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188604};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 104..128
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 282..304
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 334..352
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 122..192
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
SQ SEQUENCE 369 AA; 39676 MW; 177DCFDF9BE6C496 CRC64;
MHDLIRTIIA YVLILGLLVF VHELGHYLAA RWRGVKVETF SIGFGPALYR WHDRVGTEWR
LSAIPLGGYV KPHGFEGPED ATPEQQAAWE AGRTFHDKPV GSRVIVIAMG PVFNFVFAIL
LFTLFFALSG RPELKNEIAA VEAGSPAAQA GVKPGDVITR IGDLAVFNYA DVQAQTASHP
GLATTLGIRR NGADLTLPVT FATTPGKSPG SAPVGHLGVM AQAFPGKPMP VPKAFVAGVE
ETWTVSVETL QGLWQIVTGH RSARELGGTI RIAQMSGQVA QYGFASVVSF MALLSVNLGL
INLFPIPILD GGRLAFYAAE AIQGRPVSRR VQEISFQAGF ALIAGLFLFS TFNDLSNLGL
FNWLSKRPG
//
