ID A0A1U9NLL4_9BACT Unreviewed; 846 AA.
AC A0A1U9NLL4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:AQT68832.1};
GN ORFNames=STSP2_02008 {ECO:0000313|EMBL:AQT68832.1};
OS Anaerohalosphaera lusitana.
OC Bacteria; Planctomycetota; Phycisphaerae; Sedimentisphaerales;
OC Anaerohalosphaeraceae; Anaerohalosphaera.
OX NCBI_TaxID=1936003 {ECO:0000313|EMBL:AQT68832.1, ECO:0000313|Proteomes:UP000189674};
RN [1] {ECO:0000313|Proteomes:UP000189674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST-NAGAB-D1 {ECO:0000313|Proteomes:UP000189674};
RA Spring S., Bunk B., Sproer C.;
RT "Comparative genomics and description of representatives of a novel lineage
RT of planctomycetes thriving in anoxic sediments.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP019791; AQT68832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U9NLL4; -.
DR STRING; 1936003.STSP2_02008; -.
DR KEGG; alus:STSP2_02008; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000189674; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189674};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 599..802
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 846 AA; 91120 MW; 1A73CFC40209944F CRC64;
MDQIRQQLKL LDEQLAERRS LFDFFMSRSP LFLLAVGLTA GIAVQHLCGL NAVFWFIAIV
VLAGAAVLVS RWDAGGGRSV AFIAIALFMG IGAVRVASYE TLPGNHITRV AGEERTLATL
RGRVCSKVFT PGRDAWAFSG WGFNKPGSSF YLECESVKTR GGFAAVSGKV RVQVNSKVRS
VQCGDLVELH CWLDRFSPPT NPGEFDFQAY LARRNIHVGA SVNGAGSIRV VESNGWASLP
GVRVRLADLF REQLIEDGCA GMQTRGLIEA LLLGNRSNID AETHAAFRKT GLAHFISLSG
MHIGMFAYFV WVLCRHAGFL KTARAMILMG VVGVYVLAVP SRPPTTRAAI LCFFFALSVI
VNRKPNALNT LGLAGICLLL YRPTQLFNAG FQLSFATVLG IILLQPRLHS FANRVVGDRL
GELYAASSVG AAKFAIWVGR HMLELLTVGA AAWIGGAAII LYHFGSVSGA SAVWTVFAYP
LVLAIIAGSM VQILAGMVFP TVGVALSVFV DSMAECLIWL VRFLAEIDVT ALRVGEVAIW
MVVVYYAGVL FMRFGQYRRR VLRRMGVSAA CVGVLLPFGV NLLARGEDGL RLTVLNVGHG
QAVLLETPSG ENMLFDAGSL TRNDIGSRVV VPFLQHRGID RLDAVCISHE DIDHLNGLPE
IVEQCDVERI LGNRGVIESD SATASFLRDA VAERGGSLTL LDGGLLDGGS VKIDVIWPVE
SAAGDIALSD NDSSSVFLVR FAGRSILISS DIEEYAQGGI MERYPDLGAD VLILPHHGST
THLVESFVQS LEPEVVIASC SRGRLNSVYR PDFDGDHYAT ASHGAVTVEI GVDGDVSACG
HLRPGE
//
