ID A0A1U9ZR31_9ACTN Unreviewed; 657 AA.
AC A0A1U9ZR31;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:AQZ60412.1};
GN ORFNames=BKM31_01775 {ECO:0000313|EMBL:AQZ60412.1};
OS Nonomuraea sp. ATCC 55076.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ60412.1, ECO:0000313|Proteomes:UP000190797};
RN [1] {ECO:0000313|Proteomes:UP000190797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX PubMed=28626548; DOI=10.1039/c6md00637j;
RA Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA Seyedsayamdost M.R.;
RT "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT date and the kistamicin biosynthetic gene cluster.";
RL Med. Chem. Commun. 8:780-788(2017).
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; CP017717; AQZ60412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1U9ZR31; -.
DR STRING; 1909395.BKM31_01775; -.
DR KEGG; noa:BKM31_01775; -.
DR Proteomes; UP000190797; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:AQZ60412.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000190797}.
FT DOMAIN 14..286
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 657 AA; 71117 MW; 26947A8AE5D54942 CRC64;
MPDSHLPPVD ELLSIAVSAL GGSERQGQLT MVRAVQKAID DEEHLAVQAG TGTGKSLAYL
VPSIRHAMDS DRPVVISTAT IALQRQLVDR DLPRLSEALA KELPHEPTFA ILKGRRNYLC
RYKATAGWPE EDEQDQLFDP REVSATGRMV QRIQEWAEET ETGDRDELVP GVSEQAWRQF
SVSAQECLGA NRCPSGAECF AELARARAGE VDVVVTNHAL LAIDAMGDLP VLPEHEVVVV
DEAHELVDRV TSVVTGELSE ASVMLAVRRV GRLIDQPVAD QLMEAGEDLK ALLAAAPPGR
IDELPQVLGL TLQLIRDTAW RCITAMGPRN ADKDDPDKAG QRKAAFTALD EVHDTAVRML
DAYGHASEAD RAEVVWLDAG TDRRPPCLRV APLTVSGMLR DKLFGERTVV LTSATLALGG
TFDALAAQWG LADGKWQGID VGSPFDHPRA GILYVAKHLP QPGRDGLPQQ YLDEIAELIE
AAGGRTLGLF SSMRAAKAAT EALRDRLDVP LLCQGDDSTM LLVKQFAEDE PTCLFGTLSL
WQGVDVPGPS LRLVIIDRVP FPRPDDPLTS ARQRHVAARG GNGFMAVAAN HAALLLAQGA
GRLLRSQNDK GVIAVLDPRL ATARYSGFLL NSLPPFWRTM DPAIPRAALK RLAAEPS
//
