ID   A0A1U9ZRK0_9ACTN        Unreviewed;       506 AA.
AC   A0A1U9ZRK0;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Squalene cyclase C-terminal domain-containing protein {ECO:0000259|Pfam:PF13243};
GN   ORFNames=BKM31_02760 {ECO:0000313|EMBL:AQZ60577.1};
OS   Nonomuraea sp. ATCC 55076.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ60577.1, ECO:0000313|Proteomes:UP000190797};
RN   [1] {ECO:0000313|Proteomes:UP000190797}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX   PubMed=28626548; DOI=10.1039/c6md00637j;
RA   Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA   Seyedsayamdost M.R.;
RT   "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT   date and the kistamicin biosynthetic gene cluster.";
RL   Med. Chem. Commun. 8:780-788(2017).
CC   -!- SIMILARITY: Belongs to the terpene synthase family.
CC       {ECO:0000256|ARBA:ARBA00006333}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017717; AQZ60577.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1U9ZRK0; -.
DR   STRING; 1909395.BKM31_02760; -.
DR   KEGG; noa:BKM31_02760; -.
DR   Proteomes; UP000190797; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.50.10.160; -; 1.
DR   Gene3D; 1.50.10.20; -; 1.
DR   InterPro; IPR001330; PFTB_repeat.
DR   InterPro; IPR032696; SQ_cyclase_C.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   PANTHER; PTHR31739; ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR31739:SF4; ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF00432; Prenyltrans; 2.
DR   Pfam; PF13243; SQHop_cyclase_C; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190797}.
FT   DOMAIN          333..432
FT                   /note="Squalene cyclase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13243"
SQ   SEQUENCE   506 AA;  53967 MW;  5EA4F1C5A35C7334 CRC64;
     MSIGEALDLT AQADELVTSL MLRPWGQVSP SVYETGRLVS LAPWLTGHQE RIDYLIRTQR
     PDGSWGAPDG YGVVPTLSAT EGLLAALTRR DQEAGRDRLA DAAQRGLRVL TTWLSGPLDL
     PDMPAIEHIV PSLVARINEH VEGSPVPLPP AMSYDALHLV RSRVRSGKEV PEKLLHALEI
     AADAAAQAPG IRPTPIGSVG ASPAATAAWL GERAEPDAHE PARGHLEAVV RLFGGPVPVG
     LPITVFERGW VLSWLLRAGV TVDVPPEMVA DIRAAIGPSG TPAGPGLPAD ADTTSVALYA
     LALLGAPHEP ESLWAFRSGT HFATWPGEQG VSVSVNAHVL DAFGEYVRRR PAAAPRYAPA
     IGELAAWIRE RQRPDGSWTD RWHASPYYAT ASCALALDAF GGEASRESVR AAAEWVLATQ
     RPDGSWGRWE GTAEESAYAI QTLLLTGGSA EPRRLRAAER GQPHLVDPAG GEHPPLWHDK
     DLYVPRAVAR AAVIASSHLV RQALAG
//