ID A0A1V0A092_9ACTN Unreviewed; 424 AA.
AC A0A1V0A092;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:AQZ63618.1};
GN ORFNames=BKM31_21070 {ECO:0000313|EMBL:AQZ63618.1};
OS Nonomuraea sp. ATCC 55076.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ63618.1, ECO:0000313|Proteomes:UP000190797};
RN [1] {ECO:0000313|Proteomes:UP000190797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX PubMed=28626548; DOI=10.1039/c6md00637j;
RA Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA Seyedsayamdost M.R.;
RT "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT date and the kistamicin biosynthetic gene cluster.";
RL Med. Chem. Commun. 8:780-788(2017).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
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DR EMBL; CP017717; AQZ63618.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V0A092; -.
DR STRING; 1909395.BKM31_21070; -.
DR KEGG; noa:BKM31_21070; -.
DR OrthoDB; 5526311at2; -.
DR Proteomes; UP000190797; Chromosome.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000190797}.
FT SITE 248
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 424 AA; 47232 MW; D8B4FEB67B681BBB CRC64;
MSDGSAERAG AEWFRAARFG LFVHFGLYSL AARHEWVRSR EAMSDADYDR YLERFDPDLF
DAAALARAAR EAGMRYAVLT AKHHDGFCLF GSALTDYTSV RAAGRDLVAE FAEAMRAEGL
RVGLYYSLLD WRHPDFTIDR YHPLRDSVPP EEAKGHDMAR YRAYLHGQVR ELLTGYGPVD
LLFFDFTYPA KGPEEWGAAE LMAMVRELSP GIVVNDRLGI PGDYVTPEQY QPDAPLTRDG
AEVMWEACHT LNGSWGYDRD NHDYKSPDLL VRMLVQSVAC GGNLLLNVGP TGRGALDPRA
AETLRAIGAW TSLHARAVHG AGPSAYEPPP NALYTQRGDR LYLHLLAWPL KHVHLPGLAG
RVRYAQFLHD GSEVRMRELD GGEHEHNNLA PPGREPGTLT LTLPVVRPDV LLPVVELVLH
GEEP
//
