ID   A0A1V0A1I7_9ACTN        Unreviewed;       398 AA.
AC   A0A1V0A1I7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Sugar kinase {ECO:0000313|EMBL:AQZ64058.1};
GN   ORFNames=BKM31_23650 {ECO:0000313|EMBL:AQZ64058.1};
OS   Nonomuraea sp. ATCC 55076.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ64058.1, ECO:0000313|Proteomes:UP000190797};
RN   [1] {ECO:0000313|Proteomes:UP000190797}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX   PubMed=28626548; DOI=10.1039/c6md00637j;
RA   Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA   Seyedsayamdost M.R.;
RT   "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT   date and the kistamicin biosynthetic gene cluster.";
RL   Med. Chem. Commun. 8:780-788(2017).
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
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DR   EMBL; CP017717; AQZ64058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V0A1I7; -.
DR   STRING; 1909395.BKM31_23650; -.
DR   KEGG; noa:BKM31_23650; -.
DR   OrthoDB; 3523179at2; -.
DR   Proteomes; UP000190797; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF12802; MarR_2; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:AQZ64058.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190797};
KW   Transferase {ECO:0000313|EMBL:AQZ64058.1}.
FT   DOMAIN          19..60
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000259|Pfam:PF12802"
SQ   SEQUENCE   398 AA;  41118 MW;  F7F4109908D08296 CRC64;
     MSDPVPGTPS LLRAINDRAA LRVLLERGPL TRPQIGALTG LSKPTASQLL SRLQQAGLVV
     LDGIREGLPG RTAEVYRINP AAAYVGALDV TPDRIEARVA DITGTVVGEH TLPTPRRPHG
     ELVDRLNTAL LGAQPPDKLR RVVIGVQAAM DPTTGRLGYA AAKDVPGWHL PDLVPTLSAG
     LGVPVDVENN VNLVAVAEQA HGAARGQRDF VLLWADAGIG AAVVLGGRVH RGATGGAGEV
     GYMPAPGAPT ARESGRYADH GYQALTGGQA VLKLLRSYGV RGADFRQAVA NAVRAAAGTG
     QRAEDARAGL RDVAARLAVG LAAITAVVDP ALIVLTGGAV LPGGELLREL VEHELHALTI
     PRPPVRLSTV EGNPVLAGAL DLALDAVREE VFGSTVPM
//