ID   A0A1V0A2A2_9ACTN        Unreviewed;       536 AA.
AC   A0A1V0A2A2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:AQZ64334.1};
GN   ORFNames=BKM31_25285 {ECO:0000313|EMBL:AQZ64334.1};
OS   Nonomuraea sp. ATCC 55076.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ64334.1, ECO:0000313|Proteomes:UP000190797};
RN   [1] {ECO:0000313|Proteomes:UP000190797}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX   PubMed=28626548; DOI=10.1039/c6md00637j;
RA   Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA   Seyedsayamdost M.R.;
RT   "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT   date and the kistamicin biosynthetic gene cluster.";
RL   Med. Chem. Commun. 8:780-788(2017).
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DR   EMBL; CP017717; AQZ64334.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V0A2A2; -.
DR   STRING; 1909395.BKM31_25285; -.
DR   KEGG; noa:BKM31_25285; -.
DR   OrthoDB; 517968at2; -.
DR   Proteomes; UP000190797; Chromosome.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190797}.
FT   DOMAIN          475..527
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
SQ   SEQUENCE   536 AA;  57050 MW;  B272F64CF4944B15 CRC64;
     MSTTDDVSRR GFLTATGALL GTAALGAHSP AARARSAGPI GSGAHVAALV IGTGYGGSVA
     ALRLAQAGVD VHMIEMGKAW DTPGADGKIF CNTREPDYRS YWLRTRTKAP LNYFLGFPID
     RDIPRHTGVL DAEEFAGITV YQGRGVGGGS LVNGGMAVTP KRENFPAVLP SVDPAEMYGV
     YYPRANAGLG VATVDPAWFE TTACYQYARV GRKHAQRSGF PFVFVPDVYD WDYMEQEAAG
     SVPQSALAGE ILYGNNYGKK SLQKTYLARA AATGRVTISP LHRVTSVAPA GGSYTVTIEQ
     IDTTGAVVTT KTVTADRVFF AAGSVGTSKL LVKLKATGVL PALNGEVGKG WGDNGNVMCG
     RANHLWDPTG KLQSAIPCCG IDNWTAGGAF AEVAPLPTGI ETYASFYLSI TDNPNRARFS
     WNASAGRVEL SWQTAWKQPS IDMAKSIFDK INAKEGTIYR TDLFGVYKIW GDHLTYHPLG
     GAVLNKATDN YGRLTAYPGL YVIDGALIPG NTTVNPFVTI TALAERNIEH IIAADL
//