ID   A0A1V0A6X5_9ACTN        Unreviewed;       321 AA.
AC   A0A1V0A6X5;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=HTH arsR-type domain-containing protein {ECO:0000259|SMART:SM00418};
GN   ORFNames=BKM31_34905 {ECO:0000313|EMBL:AQZ65965.1};
OS   Nonomuraea sp. ATCC 55076.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ65965.1, ECO:0000313|Proteomes:UP000190797};
RN   [1] {ECO:0000313|Proteomes:UP000190797}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX   PubMed=28626548; DOI=10.1039/c6md00637j;
RA   Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA   Seyedsayamdost M.R.;
RT   "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT   date and the kistamicin biosynthetic gene cluster.";
RL   Med. Chem. Commun. 8:780-788(2017).
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DR   EMBL; CP017717; AQZ65965.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V0A6X5; -.
DR   STRING; 1909395.BKM31_34905; -.
DR   KEGG; noa:BKM31_34905; -.
DR   OrthoDB; 3808065at2; -.
DR   Proteomes; UP000190797; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43132; ARSENICAL RESISTANCE OPERON REPRESSOR ARSR-RELATED; 1.
DR   PANTHER; PTHR43132:SF7; HTH-TYPE TRANSCRIPTIONAL REGULATOR NMTR; 1.
DR   Pfam; PF12840; HTH_20; 1.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190797}.
FT   DOMAIN          246..318
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000259|SMART:SM00418"
SQ   SEQUENCE   321 AA;  35634 MW;  B080BB76CFBC2B90 CRC64;
     MLRIHFTGDD LRRTRLAETA DPFWEMVFTR HRLADPAPPA TLRPWLTEMR REGDRLHRYE
     RVVAALTPFG PYFPDFITPV EGLQGLDAGL QALLSTPRAR LRRELGTLAR TSPLPGWGRR
     LAEGETATLM NLAATLRAYH AIAIDPYRDT IEAAIAAETT RRRRDLTEGG PDGLLRGMAP
     LMRWRPPLLE VDYDVDRDLH LGGRGLLLIP SYFCRRVPVA LADPALPPTL VYPIDRHSHW
     ESNRTESLIA LLGATRATVL AAIDGGATTT QLAERAATSP ASVSRHTRVL RDAGLIETHR
     HGTAVLHVMT PLGRTLLSSG R
//