ID A0A1V0ACY7_9ACTN Unreviewed; 349 AA.
AC A0A1V0ACY7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Polyprenyl synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BKM31_47445 {ECO:0000313|EMBL:AQZ68090.1};
OS Nonomuraea sp. ATCC 55076.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1909395 {ECO:0000313|EMBL:AQZ68090.1, ECO:0000313|Proteomes:UP000190797};
RN [1] {ECO:0000313|Proteomes:UP000190797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55076 {ECO:0000313|Proteomes:UP000190797};
RX PubMed=28626548; DOI=10.1039/c6md00637j;
RA Nazari B., Forneris C.C., Gibson M.I., Moon K., Schramma K.R.,
RA Seyedsayamdost M.R.;
RT "Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to
RT date and the kistamicin biosynthetic gene cluster.";
RL Med. Chem. Commun. 8:780-788(2017).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP017717; AQZ68090.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V0ACY7; -.
DR STRING; 1909395.BKM31_47445; -.
DR KEGG; noa:BKM31_47445; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000190797; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000190797};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 349 AA; 37374 MW; CE489524B4628CEB CRC64;
MPVGFTQHSL GSRIDRRLSA FLDSWRNPVS DPGVEAAYGL LADFILSGGK RVRPQLCYWG
WRGAGGDDCE EIISAAAALE LCHAGLLIHD DIMDGSLLRR GHATVHRSLT DLHRGPGAEA
FGQAGGILLG TLSLAWSDAL LSSCGVESAR LRAAHHLFDA MRTEVISGQY LDVLAQLRSG
ATEAEALTVI RYKSAKYTVE RPLQIGGALA GAPLELLDAY SRFGVPLGEA FQLRDDVLGT
FGSSAETGKS ALDDLREGKQ TVMYAYAVQH ASPAQLAHLS TWHGNPGLTE ERAAEVRQIL
IDTGALARVE SMIEERVRAA MSALAEAQIK PEAAAVLALM ADQLAHRTK
//
