ID A0A1V0GMU4_9RHOB Unreviewed; 188 AA.
AC A0A1V0GMU4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Elongation factor P {ECO:0000256|HAMAP-Rule:MF_00141};
DE Short=EF-P {ECO:0000256|HAMAP-Rule:MF_00141};
GN Name=efp {ECO:0000256|HAMAP-Rule:MF_00141,
GN ECO:0000313|EMBL:ARC35176.1};
GN ORFNames=A6J80_01235 {ECO:0000313|EMBL:ARC35176.1}, FOB51_02430
GN {ECO:0000313|EMBL:QEU06954.1}, H7K23_13945
GN {ECO:0000313|EMBL:MBY0137171.1}, PY32053_04509
GN {ECO:0000313|EMBL:AYF04008.1}, PYTT13_17820
GN {ECO:0000313|EMBL:ATQ57738.1};
OS Paracoccus yeei.
OG Plasmid pTT13-1 {ECO:0000313|EMBL:ATQ57738.1},
OG Plasmid pYEE4 {ECO:0000313|EMBL:AYF04008.1},
OG Plasmid ptt13-1 {ECO:0000313|Proteomes:UP000229314},
OG Plasmid pyee4 {ECO:0000313|Proteomes:UP000272010},
OG Plasmid unnamed1 {ECO:0000313|EMBL:ARC35176.1}, and
OG Plasmid unnamed3 {ECO:0000313|EMBL:QEU06954.1}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=147645 {ECO:0000313|EMBL:ARC35176.1, ECO:0000313|Proteomes:UP000191257};
RN [1] {ECO:0000313|Proteomes:UP000191257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_252 {ECO:0000313|Proteomes:UP000191257};
RC PLASMID=Plasmid unnamed1 {ECO:0000313|Proteomes:UP000191257};
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Tallon L.,
RA Sadzewicz L., Sengamalay N., Ott S., Godinez A., Nagaraj S., Nadendla S.,
RA Geyer C., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ATQ57738.1, ECO:0000313|Proteomes:UP000229314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TT13 {ECO:0000313|EMBL:ATQ57738.1,
RC ECO:0000313|Proteomes:UP000229314};
RC PLASMID=Plasmid ptt13-1 {ECO:0000313|Proteomes:UP000229314}, and
RC pTT13-1 {ECO:0000313|EMBL:ATQ57738.1};
RA Lee K., Lim J.Y., Hwang I.;
RT "Complete genome sequence of Paracoccus yeei TT13 isolated from human
RT skin.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ARC35176.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FDAARGOS_252 {ECO:0000313|EMBL:ARC35176.1};
RC PLASMID=unnamed1 {ECO:0000313|EMBL:ARC35176.1};
RA Campos J., Goldberg B., Tallon L., Sadzewicz L., Sengamalay N., Ott S.,
RA Godinez A., Nagaraj S., Vyas G., Aluvathingal J., Nadendla S., Geyer C.,
RA Nandy P., Hobson J., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AYF04008.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCUG 32053 {ECO:0000313|EMBL:AYF04008.1};
RC PLASMID=pYEE4 {ECO:0000313|EMBL:AYF04008.1};
RX PubMed=30410477; DOI=10.3389/fmicb.2018.02553;
RA Lasek R., Szuplewska M., Mitura M., Decewicz P., Chmielowska C., Pawlot A.,
RA Sentkowska D., Czarnecki J., Bartosik D.;
RT "Genome Structure of the Opportunistic Pathogen Paracoccus yeei
RT (Alphaproteobacteria) and Identification of Putative Virulence Factors.";
RL Front. Microbiol. 9:2553-2553(2018).
RN [5] {ECO:0000313|Proteomes:UP000272010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 32053 {ECO:0000313|Proteomes:UP000272010};
RC PLASMID=pyee4 {ECO:0000313|Proteomes:UP000272010};
RA Lasek R., Szuplewska M., Mitura M., Decewicz P., Chmielowska C., Pawlot A.,
RA Sentkowska D., Czarnecki J., Bartosik D.;
RT "Genome Structure of the Opportunistic Pathogen Paracoccus yeei
RT (Alphaproteobacteria) and Identification of Putative Virulence Factors.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:QEU06954.1, ECO:0000313|Proteomes:UP000324507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_643 {ECO:0000313|EMBL:QEU06954.1,
RC ECO:0000313|Proteomes:UP000324507};
RC PLASMID=unnamed3 {ECO:0000313|EMBL:QEU06954.1,
RC ECO:0000313|Proteomes:UP000324507};
RA Sciortino C., Tallon L., Sadzewicz L., Vavikolanu K., Mehta A.,
RA Aluvathingal J., Nadendla S., Nandy P., Geyer C., Yan Y., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:MBY0137171.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S/N-202-OC-B2 {ECO:0000313|EMBL:MBY0137171.1};
RA Seuylemezian A., Singh N.K., Wood J., Venkateswaran K.;
RT "Fungal Genomes of the International Space Station.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in peptide bond synthesis. Stimulates efficient
CC translation and peptide-bond synthesis on native or reconstituted 70S
CC ribosomes in vitro. Probably functions indirectly by altering the
CC affinity of the ribosome for aminoacyl-tRNA, thus increasing their
CC reactivity as acceptors for peptidyl transferase. {ECO:0000256|HAMAP-
CC Rule:MF_00141}.
CC -!- PATHWAY: Protein biosynthesis; polypeptide chain elongation.
CC {ECO:0000256|ARBA:ARBA00004815, ECO:0000256|HAMAP-Rule:MF_00141}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00141}.
CC -!- SIMILARITY: Belongs to the elongation factor P family.
CC {ECO:0000256|ARBA:ARBA00009479, ECO:0000256|HAMAP-Rule:MF_00141,
CC ECO:0000256|RuleBase:RU004389}.
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DR EMBL; CP020441; ARC35176.1; -; Genomic_DNA.
DR EMBL; CP024423; ATQ57738.1; -; Genomic_DNA.
DR EMBL; CP031082; AYF04008.1; -; Genomic_DNA.
DR EMBL; JACLBQ010000045; MBY0137171.1; -; Genomic_DNA.
DR EMBL; CP044080; QEU06954.1; -; Genomic_DNA.
DR KEGG; pye:A6J80_01235; -.
DR eggNOG; COG0231; Bacteria.
DR UniPathway; UPA00345; -.
DR Proteomes; UP000191257; Plasmid unnamed1.
DR Proteomes; UP000229314; Plasmid ptt13-1.
DR Proteomes; UP000272010; Plasmid pyee4.
DR Proteomes; UP000324507; Plasmid unnamed3.
DR Proteomes; UP000756578; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd04470; S1_EF-P_repeat_1; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR HAMAP; MF_00141; EF_P; 1.
DR InterPro; IPR015365; Elong-fact-P_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR020599; Transl_elong_fac_P/YeiP.
DR InterPro; IPR013185; Transl_elong_KOW-like.
DR InterPro; IPR001059; Transl_elong_P/YeiP_cen.
DR InterPro; IPR013852; Transl_elong_P/YeiP_CS.
DR InterPro; IPR011768; Transl_elongation_fac_P.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR NCBIfam; TIGR00038; efp; 1.
DR PANTHER; PTHR30053:SF14; EFP_N DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30053; ELONGATION FACTOR P; 1.
DR Pfam; PF01132; EFP; 1.
DR Pfam; PF08207; EFP_N; 1.
DR Pfam; PF09285; Elong-fact-P_C; 1.
DR PIRSF; PIRSF005901; EF-P; 1.
DR SMART; SM01185; EFP; 1.
DR SMART; SM00841; Elong-fact-P_C; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
DR PROSITE; PS01275; EFP; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00141};
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768, ECO:0000256|HAMAP-
KW Rule:MF_00141}; Plasmid {ECO:0000313|EMBL:ARC35176.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_00141}; Reference proteome {ECO:0000313|Proteomes:UP000191257}.
FT DOMAIN 68..122
FT /note="Translation elongation factor P/YeiP central"
FT /evidence="ECO:0000259|SMART:SM01185"
FT DOMAIN 130..185
FT /note="Elongation factor P C-terminal"
FT /evidence="ECO:0000259|SMART:SM00841"
SQ SEQUENCE 188 AA; 20691 MW; B3ECBB6EEAE40F62 CRC64;
MKVIASSLRK GNVVEIDGKL YVVLTATNFH PGKGTPTTQV DLRRISDGNK VSERWKTTEQ
VERAHVDERA YNFLYEDGEG FHFMEPESYE QVTVSPDVVG DDKVFLEDGI SVFLQVHNGV
AIAIELPQKV TVEVVETEPV VKGQTASSSY KPAVAHNGVR IMVPPHIGVG TKVIINTADL
TYVERAKA
//
