ID A0A1V0PST7_9RHOB Unreviewed; 420 AA.
AC A0A1V0PST7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Cytosine-specific methyltransferase {ECO:0000256|RuleBase:RU000417};
DE EC=2.1.1.37 {ECO:0000256|RuleBase:RU000417};
GN ORFNames=RGUI_1072 {ECO:0000313|EMBL:ARE39213.1};
OS Rhodovulum sp. P5.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodovulum.
OX NCBI_TaxID=1564506 {ECO:0000313|EMBL:ARE39213.1, ECO:0000313|Proteomes:UP000191808};
RN [1] {ECO:0000313|EMBL:ARE39213.1, ECO:0000313|Proteomes:UP000191808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P5 {ECO:0000313|EMBL:ARE39213.1,
RC ECO:0000313|Proteomes:UP000191808};
RA Tang K.;
RT "Shallow-sea hydrothermal system.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-
CC methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:11370,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:85452, ChEBI:CHEBI:85454; EC=2.1.1.37;
CC Evidence={ECO:0000256|ARBA:ARBA00000743,
CC ECO:0000256|RuleBase:RU000417};
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016, ECO:0000256|RuleBase:RU000416}.
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DR EMBL; CP015039; ARE39213.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V0PST7; -.
DR STRING; 1564506.RGUI_1072; -.
DR REBASE; 196052; M.RspP5ORF1072P.
DR KEGG; rhc:RGUI_1072; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000191808; Chromosome.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd00315; Cyt_C5_DNA_methylase; 1.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 3.90.120.30; -; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018117; C5_DNA_meth_AS.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR46098; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR46098:SF1; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR Pfam; PF13560; HTH_31; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00094; C5_MTASE_1; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000191808};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 137
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 420 AA; 46674 MW; CCBBE18E878A93D1 CRC64;
MEFTELREET GLSVPEVAGL LGRPPRTVYN WEEGKGGPKP AEIEKLLAAK PTPKIPAGEP
SFRFIDLFAG IGGLRRAFDM ETGVGGECVF TSEWDKYARI TYSQNYGEPE DEIAGDITQI
SETDIPQHEV LLAGFPCQPF SIAGVSKKNA LNRPHGFACE YQGNLFFDVA RIVRHHRPKA
ILLENVRNLA NHDKGRTFNV IRSTLEDDLE YDIFPMILDA KSWVPQHRER IFIVGFPRER
GIKDFSLQSL KDRDPLSGPK LGTILHPEDG SEKAEGHFTV GPKAEVSDKY TLSEHLWGYL
QDYAAKHRAK GNGFGFGLNG PEDVARTLSA RYYKDGSEIL IRRPSGPPRR LTPRECARLM
GFDKPGESKF RIKVSDTQAY KQFGNAVVAP VATDVARLML PHIAEVAGVA EAAQEALEIA
//
