ID   A0A1V1HYX2_9FIRM        Unreviewed;       596 AA.
AC   A0A1V1HYX2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Peptidase, M24 family {ECO:0000313|EMBL:CED93077.1};
GN   ORFNames=CRIB_320 {ECO:0000313|EMBL:CED93077.1};
OS   Romboutsia ilealis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Romboutsia.
OX   NCBI_TaxID=1115758 {ECO:0000313|EMBL:CED93077.1, ECO:0000313|Proteomes:UP000245622};
RN   [1] {ECO:0000313|EMBL:CED93077.1, ECO:0000313|Proteomes:UP000245622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB {ECO:0000313|EMBL:CED93077.1,
RC   ECO:0000313|Proteomes:UP000245622};
RA   Hornung B.V.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
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DR   EMBL; LN555523; CED93077.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V1HYX2; -.
DR   Proteomes; UP000245622; Chromosome chr1.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245622}.
FT   DOMAIN          5..129
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          309..527
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          536..596
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
SQ   SEQUENCE   596 AA;  68980 MW;  69F7055DCA16B0A5 CRC64;
     MIKQRIEKIR DLMKEKNIYA YIVPSSDYHQ SEYVGDYFKS REFMSGFTGS AGTLIISMDE
     AGLWTDGRYF IQAENELKDS GIKLFKMGEE GVPTIEEYLL EKLPKNSTLG FDGRVMSVKE
     GQSLASKLSF KGINIEYKYD LVNDIWKERC SLPTEKAFLL DIEYSGENFS DKLSRIRTVM
     KEKKATIHIL ASLDDIAWLF NIRGRDIKSN PVVLSYAIIG IDSVYLFIDK NKISEDIRTE
     LSKENVQIKG YEEVYEFIKN IDENEVVLID TSKVNYAIYN NIPSNVRKIE ERNPSTLFKS
     IKNKIELKNI RNSHIKDGVA FTKFMYWLKN NIGKMEITEI SATQKLEDFR REQEKFIEPS
     FSTIAAYKEH AAMMHYSATE ESNYKLEPRD LFLVDSGGQY FDGTTDITRT IALGPIPKHV
     RRDFTNVVRG MIRLSKAKFL YGCRGYNLDI LARGPLWEEG IDYKCGTGHG IGFVLNVHEG
     PNGFRWKVRE GIDDNCILEE GMVTTNEPGV YVENSHGIRI ENEIVVRKSD KNEYGQFMDF
     EVITFAPIDL DAIDESLILE DERIYLNNYH KQVYDKISPY LNEEEKHWLK TYTREI
//