ID   A0A1V1I171_9FIRM        Unreviewed;      1215 AA.
AC   A0A1V1I171;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Efflux pump {ECO:0000313|EMBL:CED93970.1};
GN   ORFNames=CRIB_1361 {ECO:0000313|EMBL:CED93970.1};
OS   Romboutsia ilealis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Romboutsia.
OX   NCBI_TaxID=1115758 {ECO:0000313|EMBL:CED93970.1, ECO:0000313|Proteomes:UP000245622};
RN   [1] {ECO:0000313|EMBL:CED93970.1, ECO:0000313|Proteomes:UP000245622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB {ECO:0000313|EMBL:CED93970.1,
RC   ECO:0000313|Proteomes:UP000245622};
RA   Hornung B.V.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LN555523; CED93970.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V1I171; -.
DR   Proteomes; UP000245622; Chromosome chr1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 2.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 3.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR   Pfam; PF00873; ACR_tran; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245622};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        534..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        560..580
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        586..610
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        631..651
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        663..686
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        720..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1048..1067
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1074..1094
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1100..1125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1146..1165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1177..1200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          200..301
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          336..395
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1215 AA;  132835 MW;  24E781B1962A12AF CRC64;
     MIPKYSVKRP FTVAVAVVMV FILGIVSFFD MKTDLLPSID LPYAMVLTQY PGASPEKVEM
     SVTKPIEQVV STVSGVKNVS STSSENASMV MIEFDQNVNM DSAILDVNSK LDLVKSSFED
     GVGSSSVMKL NPDSMPVMML SVDIKGMDIK ELSNYVSENI VPKFERTNGV GSVSVTGLLE
     EKIQINLDND KISSVNKKVK SKIDNEMAEQ EKKLKDSQNQ IANGKSQLEE QSKIQKENLV
     NAEVELQSAK IKLELLASQL TSQGMNKETL NKTIEDTSKA LKDAENKLND LQNELNNPSQ
     NNEEYIMQIQ ARITVLNTTI ENLKQGITTA KQGLEVLNSL DNIKEQEKQL KIAQNKVSEE
     LNKASLELSQ GESELKKASN ELKAAKEQAY EASDMTNKIT PEMISNIVMA QNFAMPAGYV
     SGDDSKHLVK VGDKLSSIEE LENLLLFDIN GVGKIYLKDV ADISKVDNSE ETYANINGND
     GVMISLQKSS VSSTTEVTKN IGKTIDDIMK ENDKVNITTL MDQGIYIEMI IDSVLDNLIV
     GGALAIIVLL VFLKSFRPTI IIALSIPISL FVSMVLMYFS NITLNIISLS GLSLGVGMLV
     DNSIVVIENI SKMREKGMSA AKASVYGAKQ VSGAIFASTL TTICVFLPIV FADGITKQIF
     TDMGLTIGYS LLSSLIVSLT VVPAMSSKLL EKVEKKPSIL FDRLINLYEK ALRWALKHKV
     IVILPVVVLL VFSVYKIGSM GTSFMPSMDS TEMSATLEMP IGSSKKDTIK MSDKIINNLM
     KIDDIETIGA TDSTNSMLGQ ASDTTMSFFI KLKEDKKRSN TEIAKIIEER TKDFDCELKV
     SASNMDMGAL AGSGIQVIIK GEDLDELKSM AIDISKEIKP IKGIKEITTG LENPSKETRI
     IVDKNKAMEY GLTTAQIYQT ISNEIKTDTS STILTIGRND YPVIVSNGDS LTKNELKNLT
     ITGTKDNEKV DVKISSIVSI SDDESLSSIS RENQSRYMTV TATIDSDYNV GLVGKEVKSK
     LDNYKVKDGY SIEIGGEMET ISDAMGDLVL MIILAVVFVY LVMVAQFQSL LSPFIVMFTI
     PLAFTGGLLA LLITGNDLSV VSMLGFLVLS GVVVNNGIVF VDYVNQLRAT GMSKKEAIIE
     TGRSRIRPIL MTALTTILAM STMALSNGMG AEMTQGLAIV SIGGLAYSTI LTLVVIPILY
     DLMQRKEFRV IDIED
//