ID A0A1V1I1T6_9FIRM Unreviewed; 463 AA.
AC A0A1V1I1T6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Na+ driven multidrug efflux pump {ECO:0000313|EMBL:CED94097.1};
GN ORFNames=CRIB_1490 {ECO:0000313|EMBL:CED94097.1};
OS Romboutsia ilealis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Romboutsia.
OX NCBI_TaxID=1115758 {ECO:0000313|EMBL:CED94097.1, ECO:0000313|Proteomes:UP000245622};
RN [1] {ECO:0000313|EMBL:CED94097.1, ECO:0000313|Proteomes:UP000245622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIB {ECO:0000313|EMBL:CED94097.1,
RC ECO:0000313|Proteomes:UP000245622};
RA Hornung B.V.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LN555523; CED94097.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V1I1T6; -.
DR Proteomes; UP000245622; Chromosome chr1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13134; MATE_like_8; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR InterPro; IPR047135; YsiQ.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR PANTHER; PTHR42925:SF2; NA+ DRIVEN MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245622};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 463 AA; 50900 MW; 00263025C4C06A3D CRC64;
MITNTLSNYK KDKEFYIRLF VITLPIAMQS LITSSLNMLD TMMIGKIGEL ELASVGIANQ
YYFLFSLLTN AIAIGSGVLI AQLWGKKDTI NIKRTLSRSL FYSLVLTIVF MILGLIMPNK
IMAIFNNDPT VIKIGVDYLK IVVISYLFTT ITFTFASGLR SIGNTRLPML GSFIGLIVNG
VLNAILIFGL LGAPKMGIKG AALATLIARI VEFLIVVGVI YTKVDVLKLR FKDMLELPKS
LSITLNKVTL PILANEACWA LGNITYTAIY ARIGTSAAAS IQICSTVMNL FMIVTFGLAN
AAVVIIGNEI GANRESEAIS ASKKISSLSF KISILLAIVL AFLSKPIVSF FNVSVEVKIA
SEYILYVYAF ILVFKIYNAV MIVGILRGGG DATYGSILQG LTLWLIGIPL AAFAAFIIKL
PIYFVVMFAA VEEIIKVFFM MKRFKSFKWI KNMVNDEQNE VLT
//
