ID A0A1V1PQC5_9PROT Unreviewed; 177 AA.
AC A0A1V1PQC5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=peptide-methionine (R)-S-oxide reductase {ECO:0000256|ARBA:ARBA00012499};
DE EC=1.8.4.12 {ECO:0000256|ARBA:ARBA00012499};
GN ORFNames=U91I_02286 {ECO:0000313|EMBL:GAM98651.1};
OS alpha proteobacterium U9-1i.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=1605283 {ECO:0000313|EMBL:GAM98651.1, ECO:0000313|Proteomes:UP000188260};
RN [1] {ECO:0000313|EMBL:GAM98651.1, ECO:0000313|Proteomes:UP000188260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U9-1i {ECO:0000313|EMBL:GAM98651.1,
RC ECO:0000313|Proteomes:UP000188260};
RA Okano K., Furuta S., Ichise S., Miyata N.;
RT "Whole-Genome Sequences of Two Manganese(II)-Oxidizing Bacteria, Bosea sp.
RT Strain BIWAKO-01 and Alphaproteobacterium Strain U9-1i.";
RL Genome Announc. 4:e01309-16(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[thioredoxin]-disulfide + H2O + L-methionyl-[protein] =
CC [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein];
CC Xref=Rhea:RHEA:24164, Rhea:RHEA-COMP:10698, Rhea:RHEA-COMP:10700,
CC Rhea:RHEA-COMP:12313, Rhea:RHEA-COMP:12314, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:16044, ChEBI:CHEBI:29950, ChEBI:CHEBI:45764,
CC ChEBI:CHEBI:50058; EC=1.8.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001795};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAM98651.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BBSY01000002; GAM98651.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V1PQC5; -.
DR STRING; 1605283.U91I_02286; -.
DR OrthoDB; 9785497at2; -.
DR Proteomes; UP000188260; Unassembled WGS sequence.
DR GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0030091; P:protein repair; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 2.170.150.20; Peptide methionine sulfoxide reductase; 1.
DR InterPro; IPR028427; Met_Sox_Rdtase_MsrB.
DR InterPro; IPR002579; Met_Sox_Rdtase_MsrB_dom.
DR InterPro; IPR011057; Mss4-like_sf.
DR NCBIfam; TIGR00357; peptide-methionine (R)-S-oxide reductase MsrB; 1.
DR PANTHER; PTHR10173; METHIONINE SULFOXIDE REDUCTASE; 1.
DR PANTHER; PTHR10173:SF52; METHIONINE-R-SULFOXIDE REDUCTASE B3; 1.
DR Pfam; PF01641; SelR; 1.
DR SUPFAM; SSF51316; Mss4-like; 1.
DR PROSITE; PS51790; MSRB; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:GAM98651.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188260};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..177
FT /note="peptide-methionine (R)-S-oxide reductase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010722113"
FT DOMAIN 28..153
FT /note="MsrB"
FT /evidence="ECO:0000259|PROSITE:PS51790"
SQ SEQUENCE 177 AA; 19263 MW; 5C2A0EFA121C303D CRC64;
MKPLPLIIAG TVAALVAGAA LFLSQPRDAS ANAESRFEAL RTYVMDFGGT ERAFDNEYWD
HHEPGIYVEA RTGEPLFAST DKFDSGSGWP SFTRPIDVSA VAAREDSSAG MTRVEIRSKQ
GDAHLGHVFN DGPRERGGQR YCINSCAIRF IPRAEMEAQG YGAYTHLIDN PQPAPAS
//
