ID   A0A1V1PTZ1_9PROT        Unreviewed;       537 AA.
AC   A0A1V1PTZ1;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=U91I_03722 {ECO:0000313|EMBL:GAN00059.1};
OS   alpha proteobacterium U9-1i.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria.
OX   NCBI_TaxID=1605283 {ECO:0000313|EMBL:GAN00059.1, ECO:0000313|Proteomes:UP000188260};
RN   [1] {ECO:0000313|EMBL:GAN00059.1, ECO:0000313|Proteomes:UP000188260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=U9-1i {ECO:0000313|EMBL:GAN00059.1,
RC   ECO:0000313|Proteomes:UP000188260};
RA   Okano K., Furuta S., Ichise S., Miyata N.;
RT   "Whole-Genome Sequences of Two Manganese(II)-Oxidizing Bacteria, Bosea sp.
RT   Strain BIWAKO-01 and Alphaproteobacterium Strain U9-1i.";
RL   Genome Announc. 4:e01309-16(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAN00059.1}.
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DR   EMBL; BBSY01000003; GAN00059.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V1PTZ1; -.
DR   STRING; 1605283.U91I_03722; -.
DR   OrthoDB; 105971at2; -.
DR   Proteomes; UP000188260; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000188260};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        151..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..108
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
FT   REGION          509..537
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   537 AA;  58584 MW;  297DA9983E749921 CRC64;
     MADIFISYAS EDRARVRPLA EALLARGFNI WWDRSLSAGQ DYTAIIEREL KSAKAVIVTW
     TQSSVHSTFV RDEAGRARDE GRLVPVLFDK VDIPLGFGSY QAEDFTNWNG GANAPQVQLL
     EEVLKAKLSG RDVDGAAIER RRRKLGARIR LVSLLTVVAL VVGIAVGGRY LFDPPTAEVT
     QEDLRAELLR LLAEGKLTPE QAIQLASILE SGALGETQMA SNETPAGAAP APTDAATMRS
     ESEEAGVSEA QFDIASREAY RQAFLAVAQH PDAQIRLAAA QMSNPQARDA AMQTMWTYAQ
     ANPDDPLRDQ IYLLCGTVGE RNNLPLGQRA LEASVNLTPR DGQAWRMLSR SYRRTNNDQA
     AQAAETVSHA VQSEAQGDTA AAEQQLQEAA AALPDPSVQA TVVNQLGEIA VQRNDWTSAS
     ARFAQSYRLR EQVAASEPNA PAAEGALEAN AQQLVVALDR SGRTREACER LRQAQEEHNV
     AAPDQQILDR CQEEFRTRLQ PRVELSPQLQ RDGAVLRRAP STTLQRAPVE RVAPATP
//