ID A0A1V1UHG5_9RHOB Unreviewed; 654 AA.
AC A0A1V1UHG5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Cytochrome c-type biogenesis protein CcmF {ECO:0000313|EMBL:GAW35129.1};
DE Flags: Precursor;
GN Name=ccmF {ECO:0000313|EMBL:GAW35129.1};
GN ORFNames=RA2_02189 {ECO:0000313|EMBL:GAW35129.1};
OS Roseovarius sp. A-2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1570360 {ECO:0000313|EMBL:GAW35129.1, ECO:0000313|Proteomes:UP000191225};
RN [1] {ECO:0000313|EMBL:GAW35129.1, ECO:0000313|Proteomes:UP000191225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-2 {ECO:0000313|EMBL:GAW35129.1,
RC ECO:0000313|Proteomes:UP000191225};
RA Harada M., Ito K., Nakajima N., Yamamura S., Tomita M., Suzuki H.,
RA Amachi S.;
RT "Genome sequencing of bacteria contributing to the geochemical cycling of
RT arsenic, bromine, and iodine.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase. {ECO:0000256|ARBA:ARBA00037230}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|ARBA:ARBA00009186}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAW35129.1}.
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DR EMBL; BDIY01000007; GAW35129.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V1UHG5; -.
DR STRING; 1570360.RA2_02189; -.
DR OrthoDB; 9761451at2; -.
DR Proteomes; UP000191225; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR NCBIfam; TIGR00353; nrfE; 1.
DR PANTHER; PTHR43653; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43653:SF1; CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..295
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
FT DOMAIN 315..636
FT /note="Cytochrome c-type biogenesis protein CcmF C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16327"
SQ SEQUENCE 654 AA; 70966 MW; 75CB9ECA5EF56C9F CRC64;
MITELGHFAL ILAFLVACAQ AVIPLIGAHK RWPGWMAFAE PAATIQFLLT AASFAALTWA
FVTSDFSLRL VTLNSHTDKP MLYKITGVWG NHEGSMLLWV LIVTLFGGAV AWFGANLPPS
LKARVLSVQA MIGAAFFAFI LLTSNPFLRM GTPPFNGQDL NPLLQDPGLA FHPPFLYLGY
VGLSMTFSFA VAALIEGRVD AAWGRWVRPY TLAAWIFLTI GIGLGSWWAY YELGWGGFWF
WDPVENASFM PWLIAAALLH SAIVVEKRES LKSWTILLAI IAFGFSMIGA FITRSGVLTS
VHAFATDPER GVFLLGITAA FMMGALTLFA ARANVMQARG VFSMVSRESV LVLNNILLAV
ACFVVFIGTM WPLIAEMAFD RKLSVGAPFF NAAFTPFMVA LGLVLPVGAM LAWKRATVGR
IVRQLIPAFA LAVAIGALAW AMQSGRSALG PMGLFLGAWL VAGSAVDIWA RTGRGTGRLA
RLTRLPRADW GKAVAHGGLG VTMAGVAAMM AWEAEDIRVL QVGQDFEIAG YGLRLDEVHQ
EQGPNYVATK ATFTLSQNGR EIAEMQPEKR VYPVAQMPTT EAALDNAFLR DIYVVIGDPQ
EGGGWAVRSY YKPLANWIWG GSILMALGGF LSLSDRRYRV AAGARKLPQG VPAE
//
