ID A0A1V1W3X4_9ACTN Unreviewed; 1250 AA.
AC A0A1V1W3X4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:GAW54921.1};
GN ORFNames=PD653_2336 {ECO:0000313|EMBL:GAW54921.1};
OS Nocardioides sp. PD653.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=393303 {ECO:0000313|EMBL:GAW54921.1, ECO:0000313|Proteomes:UP000194147};
RN [1] {ECO:0000313|Proteomes:UP000194147}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PD653 {ECO:0000313|Proteomes:UP000194147};
RA Ito K., Takagi K., Tanaka N., Kanesaki Y., Iwasaki A.;
RT "Nocardioides sp. PD653 draft genome sequence.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAW54921.1}.
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DR EMBL; BDJG01000023; GAW54921.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V1W3X4; -.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000194147; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:GAW54921.1};
KW Hydrolase {ECO:0000313|EMBL:GAW54921.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000194147}.
FT DOMAIN 22..190
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 222..389
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1250 AA; 140363 MW; C2C5281257589396 CRC64;
MTELQITYPP ELPVTQRRED IAAAIRDHQV VIVAGETGSG KTTQLPKICL ELGRGRRTKN
GGGLIGHTQP RRIAARSVAE RIASELGTEL GDLVGYQVRF TDRTSRVSRV KLMTDGILLA
ELQRDRMLKK YDTIIIDEAH ERSLNIDFLL GYLKRLLPKR PDLKLIITSA TIDVDRFSKH
FDAPIIEVSG RTYPVEIRYR PLMAIDEEDD EGEVVVRDQT EAIVDAVKEL SAEGPGDILV
FLPGEREIRD TADALSDLPR TEIVPLYSRL SAAEQHRVFS SHGASVRRVV LATNVAETSL
TVPGIRYVVD TGVARISRYS VRTKVQRLPI EPISQASANQ RSGRCGRVEA GIAVRLYSEE
DFEGRPEFTD PEILRTNLAS VILQMTSLGL GDVARFPFVE PPDKRNVSAG VQLLEELGAL
SVGDARLTKV GRRLARLPID PRLGRMILEA ERLGCVREVI VIAAALSLQD PRERPADHQA
QADQQHARFK AEGSDFLTWL NLWRYVKEQQ QELSSSAFRR MCKREFLNYL RVREWQDFES
QLRQVAKEMD IQVGQPADSP DADGIHQALL SGLLSHIGVL EEREKERSGG RRPMREYLGA
RGAKFAIFPG SGLARKQPAY LMAGELVETS RLWARQNAAI KPEWAEQLAG DLAKRTYSEP
HWSKKRAAVL AYERVTLYGV PLVTDRLVSY GPVDRALSRE LFIRHALVYG EWHTRHRFME
TNRRLLEEAE ELEHRARRRG IVVDEHTLFD FYDARVGPDV VGGAHFDQWW KQERRQRPDL
LTFDPSMLTH DAADAISEAD YPEQWAAEGL TFPISYHFEP GTADDGLIID VPVATLNRVE
ADDFSWNVPG LREELVTSLI RSLPKSLRVN FVPAPNKARE FLAAVPAGEE PLLDALERWC
RSTTGVVVPR EAWDWTKVPE HLRPIFRVVD ESGAEQARGK DLEALKEPLR PKFAQAMAEV
ATESGLARTG ATSWVFGTIE PSFTQRRAGH EVQAFPALVD EGTTVGLQVF GSPAEQEARH
RLGVRRLLLL ELASPVKKIL DSLTNVEKLG LAGSPYPTVA ELLDDVRAAV VQAVVDARPV
VRDQASYDAI KAAAARDHEA HVRATMADVM RVLDGWRRAE KALSGRADMA LLPALTDMRA
QLERLVHRGF IGEAGATQLR RYPTYLTALE QRREKLPGQV SRDRQLMDQI AELQQAYLHQ
LDALPEGRPP GAHLREVRWM LEEYRVSLWA QQLGTAYPVS DSRIRRSLAP
//
