ID A0A1V2ESW4_9SPHN Unreviewed; 419 AA.
AC A0A1V2ESW4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Putative acyltransferase {ECO:0000313|EMBL:ONF95388.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:ONF95388.1};
GN Name=fadA_3 {ECO:0000313|EMBL:ONF95388.1};
GN ORFNames=SPHI_24800 {ECO:0000313|EMBL:ONF95388.1};
OS Sphingomonas jeddahensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1915074 {ECO:0000313|EMBL:ONF95388.1, ECO:0000313|Proteomes:UP000188729};
RN [1] {ECO:0000313|EMBL:ONF95388.1, ECO:0000313|Proteomes:UP000188729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G39 {ECO:0000313|EMBL:ONF95388.1,
RC ECO:0000313|Proteomes:UP000188729};
RA Poehlein A., Wuebbeler J.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Sphingomonas jeddahensis G39.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONF95388.1}.
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DR EMBL; MPSB01000012; ONF95388.1; -; Genomic_DNA.
DR RefSeq; WP_076745252.1; NZ_MPSB01000012.1.
DR AlphaFoldDB; A0A1V2ESW4; -.
DR STRING; 1915074.SPHI_24800; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000188729; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:ONF95388.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188729};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:ONF95388.1}.
FT DOMAIN 5..236
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 295..416
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 92
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 373
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 403
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 419 AA; 43980 MW; F1057D9A4E85E7F5 CRC64;
MTTAYIVDAV RTPRGGGKLG KGALTHLHPQ HLGATVLKAL KERNQLDTSK VDDIIWSTSQ
QRGKQGGDLG RLSALYAGYD TKASGVTLDR YCGGGISSVG FAASQIIAGF EDVVIAGGTE
MMSHHAEADS WEQGTPFAQL GRAKGNYALY DAHPISHVGV AADAIAGMEG ISREELDAFG
AESQRRAAVA MAEGRFDRSV VPVYNDDGTI ALDRDEFPRP GTTAESLAAL KPSFVAINDV
AASPDGTTMK QMIQKKYPDL EWEPVHHAGT SSGVVDGSAA LLLASEEGLK ANGWKARARI
VTAVNHGDCP TLILNAPVPA AKKALERAGL TVDDIDVWEI NEAFAVVTEK AIRDLGLDRA
KVNVNGGAIA LGHPIGATGS MLIGTALDEL ERTGGRYALI TQCAFGGMAP ALIIERVGE
//
