ID A0A1V2EU23_9SPHN Unreviewed; 773 AA.
AC A0A1V2EU23;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:ONF95808.1};
GN Name=clpA {ECO:0000313|EMBL:ONF95808.1};
GN ORFNames=SPHI_20100 {ECO:0000313|EMBL:ONF95808.1};
OS Sphingomonas jeddahensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1915074 {ECO:0000313|EMBL:ONF95808.1, ECO:0000313|Proteomes:UP000188729};
RN [1] {ECO:0000313|EMBL:ONF95808.1, ECO:0000313|Proteomes:UP000188729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G39 {ECO:0000313|EMBL:ONF95808.1,
RC ECO:0000313|Proteomes:UP000188729};
RA Poehlein A., Wuebbeler J.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Sphingomonas jeddahensis G39.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONF95808.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MPSB01000008; ONF95808.1; -; Genomic_DNA.
DR RefSeq; WP_076744777.1; NZ_MPSB01000008.1.
DR AlphaFoldDB; A0A1V2EU23; -.
DR STRING; 1915074.SPHI_20100; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000188729; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:ONF95808.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:ONF95808.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188729};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 146..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 773 AA; 84852 MW; 7585659431291DC5 CRC64;
MPSFASALET TLHKALEAAS SRRHEYATLE HLLFALVDDE HASQVMTACG VDLGEIKTTV
AHYLDTELGA LKVDQQTDPS PTSGFQRVVQ RAILHVQSSG RDEVTGANVL VALFSERESY
AVYFLQQQDM SRLDAVSFIS HGVGKGVSTP ETAASPKGAE DKEEKKPAEK GAKGESALKQ
FTVDLNEKAK NGKVDPLIGR GPEVDRTVQI LCRRSKNNPL YVGDPGVGKT AIAEGLARKI
VEGDVPDVLK PAVIYSLDMG ALLAGTRYRG DFEERLKQVV NELEKLPDAV LFIDEIHTVI
GAGATSGGAM DASNLLKPAL SGGTIRCIGS TTYKEFRNHF EKDRALLRRF QKIDVNEPTI
EDTIKILAGL RSAFETHHDV KYTPDAIKSA VELSARYIND RKLPDKAIDV IDEVGAMQML
VAPSKRKKTI TPKEIEQVIA TMARIPPKSV STDDKKVLET LDTDLKRVVF GQNKAIENLS
SAIKLSRAGL RDPEKPIGNY LFTGPTGVGK TEVAKQLATI MGIPLQRFDM SEYMERHSVS
RLIGAPPGYV GFDQGGLLTD AVDQNPHCVL LLDEIEKAHP DLFNILLQVM DNGRLTDQHG
KTVDFRNVIL IMTTNAGASD MARETLGFGN LSREGEDEQA VQRLFTPEFR NRLDAIVPFS
YLPTEVVSRV VDKFILQLEL QLADRDVHIK LDDEARQWLT AKGYDKLYGA RPMGRLIQEK
IKQPLAEELL FGKLVHGGEV VVKLKDNALA FEIVGAAPKK PKRKGGKAKV VAE
//
