ID A0A1V2GYC4_9PROT Unreviewed; 1099 AA.
AC A0A1V2GYC4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BKE38_19705 {ECO:0000313|EMBL:ONG50065.1};
OS Pseudoroseomonas deserti.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Pseudoroseomonas.
OX NCBI_TaxID=1817963 {ECO:0000313|EMBL:ONG50065.1, ECO:0000313|Proteomes:UP000188879};
RN [1] {ECO:0000313|EMBL:ONG50065.1, ECO:0000313|Proteomes:UP000188879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3 {ECO:0000313|EMBL:ONG50065.1,
RC ECO:0000313|Proteomes:UP000188879};
RA Subhash Y., Lee S.;
RT "Draft Genome sequence of Roseomonas sp. strain M3.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONG50065.1}.
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DR EMBL; MLCO01000209; ONG50065.1; -; Genomic_DNA.
DR RefSeq; WP_076959011.1; NZ_MLCO01000209.1.
DR AlphaFoldDB; A0A1V2GYC4; -.
DR OrthoDB; 341208at2; -.
DR Proteomes; UP000188879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00130; PAS; 3.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011102; Sig_transdc_His_kinase_HWE.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR Pfam; PF07536; HWE_HK; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00911; HWE_HK; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000188879};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT TRANSMEM 287..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 564..616
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 617..686
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 689..741
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 763..836
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 838..890
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT REGION 125..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 345..379
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1099 AA; 118887 MW; DD09EA7CAD73E038 CRC64;
MTGRAPPRSP TVRLHLMMLA LAALLPAWGL GFHVAGQVAD AERARLVAQA RETVQDLAFS
LEREILNMRG ELAALAASPA LRERDLATFF AEARALPLQR DAQLRLTDRQ GTLLADTGQP
FPPPEGHGAM RQPPHAPGIS NLIPSANPAR PFRIDLTQEV RSPPQGDGGN GTAAPALLLT
ASTDPARLWA AHLKRANLPE TWIAALYDGD GRQVTRMPPR PELVGALRPE DGAVAQAMSS
SALRGWARNQ SADEEPLYTV WQRVGGTPWM VLVAMPADML DGALWRALAP VLVAGALLLA
GFTAMLAFWT DRRIAVPLAR LGRMAQAFGT GAALPGFPAT RLREIDAAAE ALQAAGQERE
RLEAERIALT ARLQTVLEST TDCVLVLDGG GLLRYLNGRA ALLAGGQQGI GRPLAETFPG
WDAGPFGAAC QAAARQGLSQ SVTAFHPALG RWISADVYPS SEGITLFFRD VSDERAAQVA
LRESEARLKA VLDNVSVGVL LAEAPSGRLL LGNRRLAEML RGPISLSRGI EDYGQDWEAY
HADGSRVASE DFPLSRALRD GVPASGEYQF RAGDGSFIWI RVSGAPVRDA RAQVTGAVVA
LTDIDAERRA AAKLQDSELR FRILAEAIPQ IVWSATPDGQ IDYINPRLQD FTGLTPARAP
GALGQLVHPA DQRSTFRRWQ RALRRARPFA AELRLKRPEG GWRWCVVRAL PAFDQERQVT
RWIGAVTDVS ELAEAREALS RQVAAQAASR EAAVQAAAAL AASESRFRRF AEASPDVMWM
RDPAGTQPEF VSPAFERIWG IARERLVENP GLWLESIHPA DRDRVAAAWA QAARDGNFDA
EYRILRPDGV MRWIRDIGFP MLDAQGTMVR RGGLARDVSA AKASEARQLL LLGELNHRVK
NTLATVHSLA LQTARTAGSA ADAMPRFLND FQARLLTLSR GHDLLTARTW RGASMEDIAR
AALAPWQVED GPDGTARLSL TGPSVWLAPR QALGLALAMH ELATNATKHG ALSCAEGRVV
VTWHGTTEGL VRLDWREENG PPVKGVPSRR GFGSRMLERG LPAELGPGSA VELDYAADGF
RASIRFRPVS GPQVEEETA
//
