ID A0A1V2H4Y5_9PROT Unreviewed; 1320 AA.
AC A0A1V2H4Y5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BKE38_06830 {ECO:0000313|EMBL:ONG56119.1};
OS Pseudoroseomonas deserti.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Pseudoroseomonas.
OX NCBI_TaxID=1817963 {ECO:0000313|EMBL:ONG56119.1, ECO:0000313|Proteomes:UP000188879};
RN [1] {ECO:0000313|EMBL:ONG56119.1, ECO:0000313|Proteomes:UP000188879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3 {ECO:0000313|EMBL:ONG56119.1,
RC ECO:0000313|Proteomes:UP000188879};
RA Subhash Y., Lee S.;
RT "Draft Genome sequence of Roseomonas sp. strain M3.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00050}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONG56119.1}.
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DR EMBL; MLCO01000053; ONG56119.1; -; Genomic_DNA.
DR OrthoDB; 5287260at2; -.
DR Proteomes; UP000188879; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.180; Methylesterase CheB, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035909; CheB_C.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR011102; Sig_transdc_His_kinase_HWE.
DR InterPro; IPR000673; Sig_transdc_resp-reg_Me-estase.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF25; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF01339; CheB_methylest; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR Pfam; PF07536; HWE_HK; 1.
DR Pfam; PF13596; PAS_10; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00911; HWE_HK; 1.
DR SMART; SM00138; MeTrc; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF52738; Methylesterase CheB, C-terminal domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50122; CHEB; 1.
DR PROSITE; PS50123; CHER; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000188879};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 6..158
FT /note="CheB-type methylesterase"
FT /evidence="ECO:0000259|PROSITE:PS50122"
FT DOMAIN 212..477
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT DOMAIN 914..966
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 967..1037
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1039..1092
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT REGION 141..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 642..711
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1304..1320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1320 AA; 146802 MW; EB5A8378BDFC5903 CRC64;
MAPMMMEEAV PIVGIGVGTA SLRSLETVFA GLKSELGAAF LVAISHQGGL EVASVVRALE
RQSPMPVQIG RNDLRVERDH VYVCGPDDMM TLQSGHLRIR PASEPVGHRG TIDTMLVSIA
EQAHDRAVAV LLRGLGSAGT AGVTATKKSG GLSIGEADPG EDPQSDGAEG PLGVVDLRLP
AERIATHIAI YLTNPANAGL EDGEPVAGEA MEAQVTRITT ILRNVTSHDF HSYKRGTFLR
RVHRRMQVLQ IDSINGYVAR LRGDREEVQA LFQDLLIGVT QFFRDAQEFE VLEREIPRLF
QGKTPDDQFR VWVLGCATGE EAYSIAILLR EHMATLAQPP QVQIFATDLD ARALGLARAG
RYAASIADHI RPDRLARWFV REGDTYAVVK ELREMCIFSP HNLIKDAPFS RIDILSCRNL
LIYLNADIQA RVIPIFHFSL RAGGVLFLGS SESVTRHQKL FTPVDRRNRV FRRLDTATRT
VPDFPLSPRI RAPEPADSRN PDGAAGSRLS GSVSRQAEAI AERYAPAYVV VDRQYDILHF
SGRTGRFLEP AAGAATLNLF SLVHRDLRIE LRAALHRAVS EAARVELPRL VLRHEEKPAG
VNVIVQPVGE GDVTALVILF QDIGLLPEGP LRGDRLDHDE HVQRLENELR VTRDRLQATI
EELETTNEEL KSSNEEYQSI NEELQSANEE METSKEELQS VNEELQTVNG ELAHRVAELG
RSNSDLKNLL EATQIATVFL DNDLRVRSFT PTATEIFHLL ETDVGRPLGH VVSRVAYAEL
QEDVRRVLKT LAPIERMVVD PAHDRHYAAK VLPYRSVDNY ISGAVVTFTD LTAVHKAETA
LRESEQRLQA LLAASSEVIF RMSADWTEML DMWGGGFLAE LQDSRQWLAE LIPAEEHPRL
ATELQAAVAE RRAFELEHSV FRVDGRPGWA VWRAVPITGP DGDIIEWFGA ASDITARREA
EEAMRSSEQR LHSLVEGLPQ LVWRAREPGR WSWASRQWTD FTGQSDPDSL SWGWLEAVHP
DDRHLARDAW ARAPEQGGFV SEFRLRHGRE GAYRWFQIRA TPVRDDQGAI LEWIGSCTDI
DGLRGLQERQ TVLVAELQHR TRNLMAVVRK MAQKTARSSS DLDDFRERFR GRLDSLARVQ
GLLSRLNEHD RVTFDELVQT ELAAHGAEPG ENHRVTVGGP LGVRLRSTTV QTLAMALHEL
ATNAVKYGAL SQATAQLAIR WRIEMEAGAG AAMQPWLHVD WHESGVQMPA EPSAVQGSGQ
GRELIERALP YQLDARTTYV VGEDGIRCTI AMPVSASNMV HENDDGLDGL EQPPNPDRRG
//
