ID A0A1V2I1U3_9ACTN Unreviewed; 895 AA.
AC A0A1V2I1U3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=BL253_32100 {ECO:0000313|EMBL:ONH23718.1};
OS Pseudofrankia asymbiotica.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC Pseudofrankia.
OX NCBI_TaxID=1834516 {ECO:0000313|EMBL:ONH23718.1, ECO:0000313|Proteomes:UP000188929};
RN [1] {ECO:0000313|Proteomes:UP000188929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16386 {ECO:0000313|Proteomes:UP000188929};
RA Ghodhbane-Gtari F., Swanson E., Gueddou A., Hezbri K., Ktari K.,
RA Nouioui I., Morris K., Simpson S., Abebe-Akele F., Thomas K., Gtari M.,
RA Tisa L.S.;
RT "Frankia sp. NRRL B-16386 Genome sequencing.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONH23718.1}.
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DR EMBL; MOMC01000081; ONH23718.1; -; Genomic_DNA.
DR RefSeq; WP_076821281.1; NZ_MOMC01000081.1.
DR STRING; 1834516.BL253_32100; -.
DR Proteomes; UP000188929; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:InterPro.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06421; CESA_CelA_like; 1.
DR CDD; cd06442; DPM1_like; 1.
DR InterPro; IPR039528; DPM1-like.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 2.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000188929};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 240..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 737..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 809..833
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 839..860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..174
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 241..355
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
FT DOMAIN 537..752
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
FT REGION 871..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 895 AA; 99153 MW; 81B86257CCBF55EF CRC64;
MPEVTVVIPT RDERDNIPEL LRRLETALLA REAEILFVDD STDDTPTVIR EVAGRCRLPV
RVIHRPPPER LGGLSGAVVR GMRESRSRYV VVMDGDLQHP PEVAEALIEA VETRAADVAV
ASRYLAAGDV SGLGSASRRA ISGGSTHLTR AVFPRRIGRR CTDPMTGFFC VRRSSIDLTL
LQAAGFKILL EILARHDLRI VELPLRFGER TAGRSKASLR TGLVFLRQVA SLRLGRGVRL
ALVGLTGLCL NLAVMALLVS GGVPYLVAAV IGSEFTVASN FYLQEKIVYH DLQYRRHAWY
VRGLHFAAYN NVDMAVRTPL LVLLVNHVGT SALVAQALTI AASFVLRQSF NRRVVYRQRA
LPAGPTVPPR DDDKYRYLAG GQHRWIFYLQ AAAFVGVAVS TVGLARNARW TLGFLFPLLL
LVGEQVLALR TSTFKRRVTL PDHLFLVETY SPAHYPTIDI FLPXAGEPAD LLRNTYEHVR
RIAWPGRVEV YVLDDAGRAE VERLAASFEF NYLARPGNEY KKAGNLQYGY TRSDGDHVVI
LDADFVPRPD FLAELVPYLD GDPEVXIVQS PQYFSTTSAM SWLERCAGAT QEMFYRFIQP
SRDAVGAAIC VGTSAVYRRA ALEAIGGFPL IGHSEDVFTG VEMGRKGYRV QYVPXIVSQG
RSPDDLKAFI GQQYRWCEXS LALFSDPDFH LDTSLTGPQR ASFWSGVMYY VTTAVNSLVA
PLALLAMIWF FPSHVASSNV LPLLGALLFW LVIYPAVAHS RWRFEVLRVQ VIYGFAHLFC
LVDLLRGRTA EWVATNSGES RGRGVTTRVA VTMCVYIGLT QLATLVGLVL GVWRFGLERF
WATGALALVG SYVYLPVLWI SARSVVXRTK GETSTPAHRS TSHGRRDLST ANRAA
//
