ID   A0A1V2I8N1_9ACTN        Unreviewed;       647 AA.
AC   A0A1V2I8N1;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Glycoside hydrolase {ECO:0000313|EMBL:ONH28773.1};
GN   ORFNames=BL253_18160 {ECO:0000313|EMBL:ONH28773.1};
OS   Pseudofrankia asymbiotica.
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC   Pseudofrankia.
OX   NCBI_TaxID=1834516 {ECO:0000313|EMBL:ONH28773.1, ECO:0000313|Proteomes:UP000188929};
RN   [1] {ECO:0000313|Proteomes:UP000188929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16386 {ECO:0000313|Proteomes:UP000188929};
RA   Ghodhbane-Gtari F., Swanson E., Gueddou A., Hezbri K., Ktari K.,
RA   Nouioui I., Morris K., Simpson S., Abebe-Akele F., Thomas K., Gtari M.,
RA   Tisa L.S.;
RT   "Frankia sp. NRRL B-16386 Genome sequencing.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ONH28773.1}.
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DR   EMBL; MOMC01000037; ONH28773.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V2I8N1; -.
DR   STRING; 1834516.BL253_18160; -.
DR   OrthoDB; 9762066at2; -.
DR   Proteomes; UP000188929; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ONH28773.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000188929}.
FT   DOMAIN          101..221
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          274..345
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          386..500
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          47..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   647 AA;  70135 MW;  87504B86E165B955 CRC64;
     MRKVPGRRLA TAWPRAAATR SPLPEYPRPH LVRSSWLSLN GRWEFQGGRG PAAPATAPGH
     SGPGDHDTLS DHATSDDRGG LGDHGDPPVG QRLPGRVLVP FPVESTLSGI GTTHERMWYR
     RTFRVPPDWA VGRVHLHFGA VDWACRVWVN GVAVGAHLGG YDAFSFDITL CLNWREEEVL
     VHVFDPTDGG GQPVGKQRRH PGGIFYTSAS GIWQTVWLEP TPACHVSRLT LTPDLAAGAV
     HVVVNAVAAE DAPPAPDASI DHAAAAAPDA AVPVRVEVRA GMAAGAATVA AGTGISGQPF
     TVEIPDVRVW SPEDPFLYGV TVTLADGPSD RPGAHDRVDS YVGMRSVEVV EVSGEPRPLL
     NGRFVFHLGL LDQGYWPDGV YTAPTDDELR RDIEMAKELG FTCIRKHAKV EPARWYHWAD
     RLGMLVWQDM PSMPHDRNPD EAARERFEAE LRALVEQCRA FPSVIGWVPF NEGWGQYDVQ
     RITETVRALD PTRLISENSG SADPGNHWID AGAGDVADLH AYPGPAAVPA SAGRCRALGE
     FGGIGLPAAG HTWHSAGGFS YEWAASPGAL TDRYLGMIDE LRALFRERGL SIAIYTQATD
     VEGEYNGLVT YDRAFLKVDP NRVRAAHRQL YDDAARTISP VTGSDSE
//