ID   A0A1V2KZ87_CYBFA        Unreviewed;       969 AA.
AC   A0A1V2KZ87;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Hydantoin utilization protein A {ECO:0000313|EMBL:ONH64958.1};
GN   ORFNames=BON22_5161 {ECO:0000313|EMBL:ONH64958.1};
OS   Cyberlindnera fabianii (Yeast) (Hansenula fabianii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Cyberlindnera.
OX   NCBI_TaxID=36022 {ECO:0000313|EMBL:ONH64958.1, ECO:0000313|Proteomes:UP000189513};
RN   [1] {ECO:0000313|Proteomes:UP000189513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=65 {ECO:0000313|Proteomes:UP000189513};
RX   PubMed=28385833; DOI=10.1128/genomeA.00064-17;
RA   van Rijswijck I.M.H., Derks M.F.L., Abee T., de Ridder D., Smid E.J.;
RT   "Genome sequences of Cyberlindnera fabianii 65, Pichia kudriavzevii 129,
RT   and Saccharomyces cerevisiae 131 isolated from fermented masau fruits in
RT   Zimbabwe.";
RL   Genome Announc. 5:E00064-E00064(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ONH64958.1}.
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DR   EMBL; MPUK01000015; ONH64958.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V2KZ87; -.
DR   STRING; 36022.A0A1V2KZ87; -.
DR   VEuPathDB; FungiDB:BON22_5161; -.
DR   OMA; WYISETD; -.
DR   OrthoDB; 307246at2759; -.
DR   Proteomes; UP000189513; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 2.40.390.10; CV3147-like; 1.
DR   Gene3D; 3.40.1610.10; CV3147-like domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR048350; DUF917_C.
DR   InterPro; IPR024071; DUF917_C_sf.
DR   InterPro; IPR010318; DUF917_N.
DR   InterPro; IPR027479; DUF917_N_sf.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF10; HYDANTOINASE; 1.
DR   Pfam; PF06032; DUF917; 1.
DR   Pfam; PF20906; DUF917_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF160991; CV3147-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189513}.
FT   DOMAIN          7..182
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          205..375
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          593..755
FT                   /note="DUF917"
FT                   /evidence="ECO:0000259|Pfam:PF06032"
FT   DOMAIN          760..953
FT                   /note="DUF917"
FT                   /evidence="ECO:0000259|Pfam:PF20906"
SQ   SEQUENCE   969 AA;  104136 MW;  06F5436167AE53DC CRC64;
     MTRTLLIGVD VGGTNTDSVL IDPLLISNPD EGVISWNKAV ITKNISDGIQ EGITSLFKSR
     PDVKKEEVAS VTIGTTHFIN ALIEQDESRL ANVAVLRLCG PYSHQVPPFS DFPTGLRHIM
     EGHVGFLKGG YHVDGRSISD IDEAELLQHV EEIRSKGIKS VVVIGVFASL NHEQELKVKD
     FIVDKIPDCK VVMSHQISGV GFIERENASI INASILPFAE KIIRSFVDAV GKMGLHCPVL
     LTQNDGTVLP AIESLSCPIK TFASGTTNSM RGASFLGNVI GKTSIVVDVG GTTADVGLLL
     PTGFPRQSSS FSTVAGVRIN FSMPHVESMG LGGGSIVREI GGDIFVGPDS VGSEILKRSI
     IFDGDGSEVT ASDVAVSRDP SLAIGDPSKV STLFSNDFKS KFASRVKSML ENIIDRMKTS
     PQEIAVLAVG GGSFIVPPNL KGASEVIRPK FYNVANAIGA AMGKVSSEVH CFHKLTDTTK
     EEVLSDLKKK AISLALEKGA LESSIEVVFV SAEPIPYVDS TFEFIVKTIA DVDYHHLHSV
     SPPLASTSYN SEDVVKRPSA QPTSTGVNLD SIDYINYRPV INDKRQWVIS EVDLELLRIG
     TYILGCGGGG DPYPFFLAAR NVLRQGGSLL VVDVNDVQRY TGEDGTVGSL CCAGSPTVSN
     EQLEGPGMVS CIETMDKFSG KSSQLVFPVE IGGSNGLCPF RVSSKLGVPV VDCDLMGRAY
     PTHWQTIPSA YSKDGQPVYP PTVISNGNGN TVIISESKSD FLLEKVMRAS LSELGCTVDL
     VNPPMSAEDV QKNTIHGSLS LSWRIGRAVR ISRQTSEVYR LPEIILDAVN GSGELLFKGK
     IVGVERKLMK GHVWGEVAIE ELDGSKRKMM KIPFKNENIL ATIDDEVVCT VPDLIAVIDA
     DTGEAVGTPD YRYGLIVFVL GIAPSNKWTD TVRAIEVGGP KGFDLIDIQY KPLSTYSKPL
     SVIDEFANP
//