ID A0A1V2LYV8_9FIRM Unreviewed; 754 AA.
AC A0A1V2LYV8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Hydratase {ECO:0000313|EMBL:ONI39793.1};
GN ORFNames=AN396_06985 {ECO:0000313|EMBL:ONI39793.1};
OS Epulopiscium sp. SCG-B11WGA-EpuloA1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Candidatus Epulonipiscium.
OX NCBI_TaxID=1710701 {ECO:0000313|EMBL:ONI39793.1, ECO:0000313|Proteomes:UP000188605};
RN [1] {ECO:0000313|EMBL:ONI39793.1, ECO:0000313|Proteomes:UP000188605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCG-B11WGA-EpuloA1 {ECO:0000313|EMBL:ONI39793.1};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the aconitase/IPM isomerase family.
CC {ECO:0000256|ARBA:ARBA00007185}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONI39793.1}.
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DR EMBL; LJDB01000060; ONI39793.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V2LYV8; -.
DR STRING; 1710701.AN396_06985; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000188605; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.1060.10; Aconitase, Domain 2; 1.
DR Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR Gene3D; 3.20.19.10; Aconitase, domain 4; 1.
DR InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR InterPro; IPR015928; Aconitase/3IPM_dehydase_swvl.
DR InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR InterPro; IPR015932; Aconitase_dom2.
DR InterPro; IPR000573; AconitaseA/IPMdHydase_ssu_swvl.
DR PANTHER; PTHR43160; ACONITATE HYDRATASE B; 1.
DR PANTHER; PTHR43160:SF3; ACONITATE HYDRATASE, MITOCHONDRIAL; 1.
DR Pfam; PF00330; Aconitase; 1.
DR Pfam; PF00694; Aconitase_C; 1.
DR SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 37..468
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
FT DOMAIN 633..683
FT /note="Aconitase A/isopropylmalate dehydratase small
FT subunit swivel"
FT /evidence="ECO:0000259|Pfam:PF00694"
SQ SEQUENCE 754 AA; 82790 MW; FE21BBF564CC34A4 CRC64;
MVKLYEQGMY LLNNQEISEE CSSLSKEEAK KGTMAYEILQ AHNTSGNSEK LKIKFDAMAS
HDITFVGIIQ TAKASGLKKF PIPYVLTNCH NSLCAVGGTI NEDDHMFGLS AAKKYGGIYV
PPHIAVIHQY MREMMAGCGK MILGSDSHTR YGALGTMAIG EGGGELVKQL LSDTYDIDYP
DVVGVYLTGK PSKGVGPQDI ALAIIGKVFA NGYVKNKVME FVGPGIASLE TDFRNGIDVM
TTETTCLSSI WKTDNDTRTY LKAHGREEDY KELSPKDIAY YDGMIYVDLS QVKPMIALPF
HPSNVYEIDY LNENLEEILK TVEEEGRKII GNPNIEFNLT SKIVDGKLKV DQAIIAGCAG
GTYSNMMESA KIIKNKSCGN DELSLSVYPS SQPVMMALTQ SGALNEFMAS GAIIRTAFCG
PCFGAGDTPA NGALSIRHTT RNFPSREGAK PGNGQMSSVA LMDARSIAAT VANGGFLTPA
TDCDFEPTNY SDYKFDPTSY NNRIYNGYVK IEEDAELKYG PNIKDWPQMS RLTSNIVMKV
ASFIDDPVTT TDELIPSGET SSYRSNPLGL AEFTLSRRDP QYVGRAKAFN ELEKARVNGI
DPTTLNDELK LVFEKIKSIT KDINAMDTVL GTVVYANKPG DGSAREQAAS CQRVLGAVAN
IAKEYATKRY RSNLMNWGMV PFLIDDCNDF GLNDYIYVPN IDQILASQDL SDIKAYVIGD
EIKEIKLYIA NMTDEEKLIV RAGSLINYNK DKMK
//
