ID A0A1V2QUL3_9PSEU Unreviewed; 1041 AA.
AC A0A1V2QUL3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=ALI22I_06730 {ECO:0000313|EMBL:ONI91940.1};
OS Saccharothrix sp. ALI-22-I.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1933778 {ECO:0000313|EMBL:ONI91940.1, ECO:0000313|Proteomes:UP000188617};
RN [1] {ECO:0000313|EMBL:ONI91940.1, ECO:0000313|Proteomes:UP000188617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALI-22-I {ECO:0000313|EMBL:ONI91940.1,
RC ECO:0000313|Proteomes:UP000188617};
RX PubMed=28087533;
RA Yeager C.M., Gallegos-Graves V., Dunbar J., Hesse C.N., Daligault H.,
RA Kuske C.R.;
RT "Polysaccharide degradation capability of Actinomycetales soil isolates
RT from a semi-arid grassland of the Colorado Plateau.";
RL Appl. Environ. Microbiol. 0:0-0(2017).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONI91940.1}.
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DR EMBL; MTQP01000043; ONI91940.1; -; Genomic_DNA.
DR RefSeq; WP_077004633.1; NZ_MTQP01000043.1.
DR AlphaFoldDB; A0A1V2QUL3; -.
DR STRING; 1933778.ALI22I_06730; -.
DR Proteomes; UP000188617; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000188617}.
FT DOMAIN 518..592
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1041 AA; 111168 MW; 9A3BE92CB3692CE1 CRC64;
MSASPVATGD CLHELFAAQA ERTPDRIAVT DGRRELTYRQ LDEAADRLAG RLRAAGVGPE
VLVGLCADRN VDLVVAVLGV LKAGGGYVPL DPRYPANRLE FVLADCRCPV VVGHRRFADL
VPGVPFVALD DHTAVTPAEP AAAAAWPDNT AYVIHTSGST GTPKGVVVSH ANVTRLFAVT
RAKFGVTASD TWTLFHSYAF DFSVWELWGA LLHGGRVVVV PYETSRDPEA FWRLLIEQQV
TVLSQTPSAF RQLIRAAEAA GWPGTALRLV VFGGEALEPA MLLPWFDRFG DTTPRLINMY
GITETTVHVT VRPLTRADAA GQGSPIGVPL DDLEVGLLDP DLHTVPPGEP GEAYVGGAGV
AGGYLGRPGL TARRFVPDPA GPPGARRYRT GDLAALRDGE LAFLGRVDDQ VQFRGFRVEP
AEIEAALTAL SGVSAAAVVL HHDQDGEAYL AGFVVAAPGA EIDPRRLRAA LAERLPAHLI
PSTVTALDAL PLTANGKLDR EALRDRQAAH RIQPSRADMT GGPADVLAGI WAGVLGVERV
GPDDDFFTLG GDSMTAIRVV SQAREEHIAI SVHSLFQHPT IAGLVAAGLD GEVDGITSDA
TDTATGTAED RVYPAAFLQM GLIYEYEIND DPTLYHDVSA VRLSGPLDEV ALRRALDATS
ARHELLRTSF DLVGYLEPVQ IVHAGAPIPL TVLDAPDAAD PDEALQRWWA GQWRRPFDLT
VAPLARCHVL RHPDGAWHLA LSVHHSVVDG WSFAVVMADL LQAYDHELGE GAPLAAPAAA
RYRDFVALER KAAADPDTAA YWTTLLDGYQ PTPLWADSGA GEEALLTVPV DASLTAEVRR
LAVQSGVPPK SVYLAAHLWA LGELTGTADV LTGLVTNGRP EHIGADTVVG MFVNTLPLRL
ELPDGSWRSL VSAAFAAERA YLRHRHFPPA KLRSVTGFGA PDVLFNYADF RAYDVLGGLR
AIRAHEWWFG DRNGFPLSVT VARRPTAPEW DLSVRVGAGH GGHALAESAS GLMLNALRRI
VADPDGSAGR LNRHVAPGGA S
//
