ID A0A1V2QWP7_9PSEU Unreviewed; 344 AA.
AC A0A1V2QWP7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=3-oxoacyl-ACP synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ALI22I_02670 {ECO:0000313|EMBL:ONI92663.1};
OS Saccharothrix sp. ALI-22-I.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1933778 {ECO:0000313|EMBL:ONI92663.1, ECO:0000313|Proteomes:UP000188617};
RN [1] {ECO:0000313|EMBL:ONI92663.1, ECO:0000313|Proteomes:UP000188617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALI-22-I {ECO:0000313|EMBL:ONI92663.1,
RC ECO:0000313|Proteomes:UP000188617};
RX PubMed=28087533;
RA Yeager C.M., Gallegos-Graves V., Dunbar J., Hesse C.N., Daligault H.,
RA Kuske C.R.;
RT "Polysaccharide degradation capability of Actinomycetales soil isolates
RT from a semi-arid grassland of the Colorado Plateau.";
RL Appl. Environ. Microbiol. 0:0-0(2017).
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONI92663.1}.
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DR EMBL; MTQP01000031; ONI92663.1; -; Genomic_DNA.
DR RefSeq; WP_077003966.1; NZ_MTQP01000031.1.
DR AlphaFoldDB; A0A1V2QWP7; -.
DR STRING; 1933778.ALI22I_02670; -.
DR OrthoDB; 7055207at2; -.
DR Proteomes; UP000188617; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00827; init_cond_enzymes; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000188617}.
FT DOMAIN 109..186
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 244..335
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 344 AA; 37186 MW; D16DE34A3BC405D4 CRC64;
MRYDDLHIAG LGWFHPKTVS VEEAVADGRC EPAAAQRTQT RHVAIAGPED TQPDMAVRAG
KQALVRSGHR PEDVDLLLHA VANYNGLDGW NAASFVQHRV LGRSGVSYEI RQLSNGGVAS
IQLAAAYLEG RPGRAAMITA SDKFTEPAWN RWRSSAGLLF ADGASAVVLS RRGGFARVLS
AVTVSDPELE GLQRGNQPFH DYADPAQYPV ELEARTLEFS DLMPLDESGP RRAAGMRRAA
NQALAEADTA IEDIRRFVAP NFGFELMRLS CLVPLGIELE RTTWEWGSQV GHTGAADQFA
GLSHLVETGA VEAGDRVMVV GVGGGFNWTA AVVEITEVPD WSER
//
