ID A0A1V2RLS1_9ACTN Unreviewed; 408 AA.
AC A0A1V2RLS1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=STBA_40650 {ECO:0000313|EMBL:ONK13302.1};
OS Streptomyces sp. MP131-18.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1857892 {ECO:0000313|EMBL:ONK13302.1, ECO:0000313|Proteomes:UP000189065};
RN [1] {ECO:0000313|EMBL:ONK13302.1, ECO:0000313|Proteomes:UP000189065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP131-18 {ECO:0000313|EMBL:ONK13302.1,
RC ECO:0000313|Proteomes:UP000189065};
RA Paulus C., Rebets Y., Tokovenko B., Nadmid S., Terekhova L.P.,
RA Myronovskyi M., Zotchev S.B., Rueckert C., Kalinowski J., Luzhetskyy A.;
RT "New natural products identified by combined genomics-metabolomics
RT profiling of marine Streptomyces sp. MP131-18.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONK13302.1}.
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DR EMBL; LZNS01000001; ONK13302.1; -; Genomic_DNA.
DR RefSeq; WP_077060580.1; NZ_LZNS01000001.1.
DR AlphaFoldDB; A0A1V2RLS1; -.
DR STRING; 1857892.STBA_40650; -.
DR OrthoDB; 4035289at2; -.
DR Proteomes; UP000189065; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:ONK13302.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189065};
KW Transferase {ECO:0000313|EMBL:ONK13302.1}.
SQ SEQUENCE 408 AA; 45122 MW; 26FEDEF90870B4EE CRC64;
MTSDSASDAA ALRNQMVDTI LESRAALNRS LSGHVEAVMR KVPRHAFLPG LALKDAYAQD
APVMKRDDDG VVISSVTAPK IMAGMLHQLD IEPGHRVLEI GSGGYNAAML RELVGPDGEV
TTIDIDQDVI NRARTCLATA GYADVRALCA DGEVGAKEYA PFDRIIVTVD SWDIPPAWVE
QLAEDGRLVV PFRVLGLTRS IAFERTRDRL VSGSYELCGF VPMQGAGARG LKVVRLQEKD
VYLRVDRKHD FDAESLRAAL KQPRVEAWSG VTARRGELMD EQDLWLATVE DEFCILKATQ
EAIAQGLVHP SWRVATPALV QGGSFAYRAF PRAVDEKQTT FEFGVYAHGP DAEEVANRFA
EHLRVWDRDH RQGPGARFEV YPADTPDDHL TQGRVVNKRH TRVTISWP
//
