ID A0A1V2RUC4_9ACTN Unreviewed; 236 AA.
AC A0A1V2RUC4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Guanylate kinase {ECO:0000313|EMBL:ONK16057.1};
DE EC=2.7.4.8 {ECO:0000313|EMBL:ONK16057.1};
GN ORFNames=STBA_69070 {ECO:0000313|EMBL:ONK16057.1};
OS Streptomyces sp. MP131-18.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1857892 {ECO:0000313|EMBL:ONK16057.1, ECO:0000313|Proteomes:UP000189065};
RN [1] {ECO:0000313|EMBL:ONK16057.1, ECO:0000313|Proteomes:UP000189065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP131-18 {ECO:0000313|EMBL:ONK16057.1,
RC ECO:0000313|Proteomes:UP000189065};
RA Paulus C., Rebets Y., Tokovenko B., Nadmid S., Terekhova L.P.,
RA Myronovskyi M., Zotchev S.B., Rueckert C., Kalinowski J., Luzhetskyy A.;
RT "New natural products identified by combined genomics-metabolomics
RT profiling of marine Streptomyces sp. MP131-18.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the guanylate kinase family.
CC {ECO:0000256|ARBA:ARBA00005790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONK16057.1}.
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DR EMBL; LZNS01000001; ONK16057.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V2RUC4; -.
DR STRING; 1857892.STBA_69070; -.
DR OrthoDB; 9808150at2; -.
DR Proteomes; UP000189065; Unassembled WGS sequence.
DR GO; GO:0004385; F:guanylate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00071; GMPK; 1.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23117:SF13; GUANYLATE KINASE; 1.
DR PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ONK16057.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189065};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ONK16057.1}.
FT DOMAIN 30..208
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 236 AA; 26527 MW; 24542328EA896AAF CRC64;
MPESLPEAQA ETIPAPQPEN SRPLVTRPAG TLLVLSGPSG TGKTSLSRAM VEKDPTLATT
RSVTTRKPRG PGEEHYDYVS REVFLKMVGN GDFVQWIHPS FDEYYGTLRA PVEKALSEGQ
DLVFDYCTEG YLNLRRFYPE QVVGVFVMAP SVEAMAIRLK GRGSESPEEL VLRHHMAAKD
FAFVDQHDYH VINDDFDAAL QTLLAIRRAE QARMARQRAV LDVYAQHAEP TLLRYY
//
