ID A0A1V2SPN7_9STRE Unreviewed; 2874 AA.
AC A0A1V2SPN7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0000259|PROSITE:PS50847};
GN ORFNames=BVE84_02435 {ECO:0000313|EMBL:ONK30605.1};
OS Streptococcus azizii.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1579424 {ECO:0000313|EMBL:ONK30605.1, ECO:0000313|Proteomes:UP000188946};
RN [1] {ECO:0000313|EMBL:ONK30605.1, ECO:0000313|Proteomes:UP000188946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12-5202 {ECO:0000313|EMBL:ONK30605.1,
RC ECO:0000313|Proteomes:UP000188946};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONK30605.1}.
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DR EMBL; MSPR01000003; ONK30605.1; -; Genomic_DNA.
DR RefSeq; WP_076995501.1; NZ_MSPS01000003.1.
DR STRING; 1579424.BVE84_02435; -.
DR OrthoDB; 2203283at2; -.
DR Proteomes; UP000188946; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR041498; Big_6.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN ALPHA-1(X) CHAIN; 1.
DR Pfam; PF17936; Big_6; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF05345; He_PIG; 3.
DR SUPFAM; SSF49313; Cadherin-like; 2.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 2838..2874
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 45..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1643..1811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1832..2606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2671..2699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2764..2843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1655..1679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1680..1694
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1884..1900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1945..1961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2070..2086
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2131..2145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2198..2214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2277..2293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2323..2337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2445..2459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2570..2592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2671..2686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2764..2779
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2801..2843
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2874 AA; 305514 MW; FF63CBE1067BD1FA CRC64;
MSKRQRNKKR LRLEQKRLKA VVAAAAIGTT VGVSSPLYAE EVSPATAGAG QVAPVPAEEN
ATTEESPEVD TVSTTEVAPT VAESPAEETG AEAVVPAPLD TSSLAQTLAT LRTLLEQSAA
TNTSEKTPES LAGYEAALAT ARQEEEKAAL LLANGATSQA EVEAQDAALV AVISNLSQAK
NALVDKVVVE EGAAESSTAA TEAEKQASPD NTSRTVSLTY TVEYVNRQTG EVVFSIQKEK
AVTTTEAVAT ASVTEIGAEL TNEAALADFY VPDGLETQKT VELSEGTTTK VTYPVERFQN
FPAEAPRRVR RAAEENPVTI ELVSVSNIEN WGGFYDKSTN TWARFKFKIS GEGIESVNSS
DIYDGRYDAI TGFYEGQIWI TSGTPNTLPL RFNIRQNGVD KTVDGPSLSF LSKEDYQAHR
DRTPYMTIER YWGNNVSNVD YTVKKNGTQA QVRYKMGLTR IGTDEVELTA DAQKLGLNYD
PVSNYITGIL DFSDPALLAG SYQIGLVAKA NSGYKATALL KIEDPRTFIL RDLANGLNSG
ENPNVREYAN AAYFKNANNG GPIRTDKGND TDDYQNRDLT YEMKVTTTPF GYYISNDPNA
KKTVADATST TPQYVAGFQL LHPDSYVNFT EEVTITKFEQ TGGTSGWELE FIDRNTLANR
PFDTHLNTVG ALWYLDHVNM DKATMYSTGY DGRTNYESKY PIGPYWVLFK KMGESGTQGS
AFVTFKTTDS NGVTRNFRIN ITTVERSQDG HLTNADVRFE GNAAYTDAVT KAVLVPASSE
EQVLGKVELN KINASVVPVR FPDGTEYDAS TQTVKKKAGV TLAPGVYTFQ VRAVDGHFGD
NAPTREMSFK VVDNILAIPH QVWTEGSRID PIPVSMEHNS DITEIKVIRM GNHADLLADS
TGKTINGVAT TRTTENQTAR LQVSYRNSEG GTDTVYTDFT YEVRPNDNQL DLDVTNAIQT
VKEGQRYENM VVTHTEGAEL SVITALPKGL RFSPSTKTFS GRGVEAGTYH ITILAEKDGL
SATKSIHLTV EPGELVADDY VREVVAGDAI EELLIEKPGN ATLEFSDWNA RDLGNYGLTF
NREEATINGT TTRVGEREYT YSLVRTVNGT TQRVNGRITL RITNRPVTVT SNDQTLEVGT
AIQNFTIETT AGASIGNINT YLLPPGVTYD SDSKTFSGTP TRVGTFRIPY TASYPNIEGN
TTATGWFVLN VTDKYIGVNS GQETVTAGTA IQDFVIRPSE GGEISYISDD QLPSGVTYNR
ETKTISGRPT KVGRFVVSYT ARYPHLSGNT EATGQYVLIV TDKAINVSAG NQTTVVESQM
PNLVLTASEG AHVEIVSELP AGLSYDATTK TISGTPKKVG TYILEARASY PDLEGNIEAN
TTFSITVLPI AADVEVDRDN QQVTLGDDIT PVQVSHSRLS DLYLSTPYGD VPESSLDALF
RDQYGLRYDS ATKTISGTPS RIGTFEFRMK AKNNSDLGGA EDVETFVIKV VPADLDLVIS
NDAQTILLGS NIRNMVLTHT DGATLDFDET QLPEGLVYDA GTKTISGTPT KAGRYDIQAS
VTSEDGKRTK VAVARLDVIE LPDSVQSADP RLNKIIEGDT AVSGYGTPNA TVKVSLPDGT
VRETTVGESG TWSITDLPAF EKGQSVDAKQ TEKGKTPSDA ISATAVPQIT KGDNGQDGKS
PSVETERGKG TDAAGEEVDG TWVITKDGDG NELSRTFIPD GSKGDKGDKG EDGQNGQNGV
DGKSPSVATE RGRGTNAAGE EVDGTWVITK DGDGNELSRT FIPDGSKGDK GEDGSPGTIL
KVQRGRGKDS AGNIVDGTWI LNEYDDFLSF IPDGQNGSRG EDGKSPSVET ERGKGTNPAG
EEVDGTWVIT KDGDGNELSR TFIPDGSKGD KGDKGEDGQN GVDGKSPSVA TERGKGTNPA
GDEVDGTWVI TKDGDGNELN RTFIPDGSKG DKGDKGEDGQ NGVDGKSPSV ATERGRGTNP
AGEEVDGTWV ITKDGDGNEL SRTFIPDGSK GDKGDKGEDG QNGQNGVDGK SPSVATERGR
GTNLAGEEVD GTWVITKDGD GNELSRTFIP DGSKGDKGDK GEDGQNGQDG KSPSVATERG
KGTNPAGDEV DGTWVITKDV DGNELSRTFI PDGSKGDKGD KGDKGEAGQN GQNGVDGKSP
SVATERGRGT NPAGDEVDGT WVITKDGDGN ELTRTFIPDG SKGDKGDKGE DGQNGQDGKS
PSVATERGKG TNPAGEEVDG TWVITKDGDG NELSRTFIPD GSKGDKGDKG EDGQNGQNGV
DGKSPSVATE RGKGTNSAGE EVDGTWVITK DGDGNELSRT FIPDGSKGDK GDKGEKGEAG
QNGQNGVDGK SPSVATERGR GTNPAGDEVD GTWVITRDGD GTEIARTFIP DGQNGQNGRD
GVDGKSPSVA TERGRGTNPA GEEVDGTWVI TKDGDGNELN RTFIPDGSKG DKGDRGEDGQ
NGQDGQNGRD GVDGKSPSVA TERGRGTNAA GEEVDGTWVI TRDGDGTEIA RTFIPDGQNG
QNGRDGVDGK SPSVATERGR GTNPAGEEVD GTWVITKDGD GNELSRTFIP DGSKGDKGDK
GEDGRDGRNG IDGKSPTVEA TPGVNTEGHT GIWVIIRDGN GNEISREFVR DGKDGKTPVV
TTVPGKNTDG HTGIWVIVTD GDGREVSREF VRDGRDGRDG RDGVDGKSPT VEATPGVNTE
GHTGIWVIIR DGNGNEISRE FVRDGKDGKT PVVTTVPGKN TDGHTGIWVI VTDGDGREVS
REFVRDGIDG KDGKDGECSC INKPTEPNKP TEPSKPTNPS TPTDPNQGSL LPNMVSTKAF
TSSFPSSSHQ SATSRSQLPN TGTETLPFLN VLAFASLGLS GAMLFKNKRK EDEK
//
