ID A0A1V2TE22_9NOCA Unreviewed; 454 AA.
AC A0A1V2TE22;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Sodium:alanine symporter family protein {ECO:0000313|EMBL:ONM47770.1};
GN ORFNames=B0T46_16100 {ECO:0000313|EMBL:ONM47770.1};
OS Nocardia donostiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1538463 {ECO:0000313|EMBL:ONM47770.1, ECO:0000313|Proteomes:UP000188836};
RN [1] {ECO:0000313|EMBL:ONM47770.1, ECO:0000313|Proteomes:UP000188836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=X1655 {ECO:0000313|EMBL:ONM47770.1,
RC ECO:0000313|Proteomes:UP000188836};
RX PubMed=26914251; DOI=10.1007/s10482-016-0667-8;
RA Ercibengoa M., Bell M., Marimon J.M., Humrighouse B., Klenk H.P.,
RA Potter G., Perez-Trallero E.;
RT "Nocardia donostiensis sp. nov., isolated from human respiratory
RT specimens.";
RL Antonie Van Leeuwenhoek 109:653-660(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONM47770.1}.
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DR EMBL; MUMY01000013; ONM47770.1; -; Genomic_DNA.
DR RefSeq; WP_077117950.1; NZ_MUMY01000013.1.
DR AlphaFoldDB; A0A1V2TE22; -.
DR STRING; 1538463.B0T36_18435; -.
DR OrthoDB; 9806926at2; -.
DR Proteomes; UP000188836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000188836};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 239..266
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 348..374
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 386..403
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 415..436
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 454 AA; 47687 MW; 1EE0F9FF0ADB99A4 CRC64;
MDELLNSASG FIWGPWLLIP LLLLTGLYLT VLLRGLQIRK LGTALWLAFV KRREPDGAGD
ISHYQALSTA LAATVGVGNI AGVATAIALG GPGAVFWMWC TGLVGMATKY SEAFLGVRFR
RTDAAGEQAG GPMHYLREGI KGPFGVFLGG FFAVAGVFAS FGIGNMTQAN TVAANVESEW
GLPTWVTGLI ITGLAAAVIL GGIKNIGRVT SLFVPVMIIL YIVGAAAVLA FNVTELPAAI
GLIVTDAFTG TAATGGFVGA GVAAAIRYGV ARGIFSNESG LGTGGIAAAA AQTTHPVRQA
LVSMTQTFID TLVVVSFTGL TIVVTGVWKS DSSPATFTAD AFAQALPGTW GSVIVTVSVI
FFAFSTVLGW SYYGDRCIEY LFGRKLVLPY RIVFIVVVYL GATRELSTVW TFSDVANGLM
ALPNLIGLVI LSPLVYRETK AYFDGKQSDE VRVH
//
