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Database: UniProt
Entry: A0A1V2ZVM9_9GAMM
LinkDB: A0A1V2ZVM9_9GAMM
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ID   A0A1V2ZVM9_9GAMM        Unreviewed;       355 AA.
AC   A0A1V2ZVM9;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   08-MAY-2019, entry version 8.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=B1A74_12395 {ECO:0000313|EMBL:OOC09197.1};
OS   Thioalkalivibrio halophilus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Thioalkalivibrio.
OX   NCBI_TaxID=252474 {ECO:0000313|EMBL:OOC09197.1, ECO:0000313|Proteomes:UP000189177};
RN   [1] {ECO:0000313|EMBL:OOC09197.1, ECO:0000313|Proteomes:UP000189177}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HL17 {ECO:0000313|EMBL:OOC09197.1,
RC   ECO:0000313|Proteomes:UP000189177};
RA   Ahn A.-C., Meier-Kolthoff J., Overmars L., Richter M., Woyke T.,
RA   Sorokin D.Y., Muyzer G.;
RT   "Genomic diversity within the haloalkaliphilic genus
RT   Thioalkalivibrio.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OOC09197.1}.
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DR   EMBL; MUZR01000058; OOC09197.1; -; Genomic_DNA.
DR   RefSeq; WP_018947395.1; NZ_MUZR01000058.1.
DR   GeneID; 34137018; -.
DR   BioCyc; GCF_001995255:B1A74_RS12405-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000189177; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000189177};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189177};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       41    337       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   355 AA;  38878 MW;  A2BB1784377CC648 CRC64;
     MTADTDDLRI RDIQEVSAPD TVRDELPITD AASDTVYEAR QACHRILHGE DDRLQVIVGP
     CSIHDVDAAL DYADRLKPLR DELSDALNIV MRVYFEKPRT TVGWKGLIND PDLDGSFHIN
     KGLRVARGLL RDLAVKGMPA ATEYLDLISP QYIADLVAWG AIGARTTESQ VHRELASGLS
     CPVGFKNSTD GSLRVAIDAI RSASRPHHFL SVTKAGRSAI FSTAGNDDCH IILRGGRQPN
     YDAESIDQAC RELQMAELPE QVMVDCSHAN SRKDPAQQME VARVLGEQIA GGDRRIIGVM
     LESHLLGGRQ DILPGQPLNY GQSITDACMG WDDSEATLRG LAEAVRARRK HNTPA
//
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