ID A0A1V3A0V5_9GAMM Unreviewed; 1099 AA.
AC A0A1V3A0V5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Multidrug transporter AcrB {ECO:0000313|EMBL:OOC10961.1};
GN ORFNames=B1A74_02150 {ECO:0000313|EMBL:OOC10961.1};
OS Thioalkalivibrio halophilus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=252474 {ECO:0000313|EMBL:OOC10961.1, ECO:0000313|Proteomes:UP000189177};
RN [1] {ECO:0000313|EMBL:OOC10961.1, ECO:0000313|Proteomes:UP000189177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL17 {ECO:0000313|EMBL:OOC10961.1,
RC ECO:0000313|Proteomes:UP000189177};
RA Ahn A.-C., Meier-Kolthoff J., Overmars L., Richter M., Woyke T.,
RA Sorokin D.Y., Muyzer G.;
RT "Genomic diversity within the haloalkaliphilic genus Thioalkalivibrio.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOC10961.1}.
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DR EMBL; MUZR01000007; OOC10961.1; -; Genomic_DNA.
DR RefSeq; WP_077243644.1; NZ_MUZR01000007.1.
DR AlphaFoldDB; A0A1V3A0V5; -.
DR STRING; 252474.B1A74_02150; -.
DR OrthoDB; 9758297at2; -.
DR Proteomes; UP000189177; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF16; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189177};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..588
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 932..950
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 957..977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 989..1013
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1034..1052
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1064..1086
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1099 AA; 119667 MW; 1D4EB08AE91D3B6C CRC64;
MSGGSAEAAP ERMGISGRIA KAFLTTQITP LLALVGLLLG LFAILVTPRE EEPQINVTMA
DVFIPFPGAS AEEVAHLVST PAEQVLSEIE GMDDIYSTSR PDMAHITVQF EVGEDRTAAL
VRLYNQIFSN DDWIPQNLGV GEPMVRPMGI DDVPIVNVTL WTEDEERGGH DLLRVAHGLE
TQLKRVSGTR DIYTVGGPDH VVHVRFKPEM LAAHNLAVDD LREALAVSNF SRDAGHLYQD
DEEILIQAGD FITEPEAFAR LVVGMHDGRP VHLEDVAEVE QGPGYPSEHV RFAHGAAAEG
GGHIGQSHPA VTVAVAKQPG TNAPDIADQV IERLDQLKGS YIPEGVEVSI TRNYGQTAED
KASTLIQKLM LATASVIILV WIALGWREAF IVGVAVIITL ALTLFASWAW GFTLNRVSLF
ALIFAIGILV DDAIVVVENI HRHMVQGGRK FLESIPLAVD EVGGPTILAT FTVIAALLPM
AFVTGLMGPY MSPIPINASM GMVLSLAVAY VVTPWLTYKV LRRQGEQLEA GGGHGAHEGE
AASAGLMRLF NFVLLPFLGT GGRKKVNRMV LWGGTLVLIL GSVSLAYYQL VVLKMLPFDD
KSEFQVVLDM PEGTSLERTG QVLGEMADYL KTVPEVHDVQ TYAGTATPIN FNGLVRQYYL
REGSHVGDIQ VNLVHDSERD RRSHDIALSV RDEINAIAGR YDGAAVKVVE VPPGPPVMSP
IVAEIYGPDY DGQIEVAKQV REVFEDTEGL TDIDDSVEHP GPKKILQVDR ERAAHLGVPQ
MAVVEAIDTA LSGEDVTYLY GSNIKYAVPV RLEFDRAEKG SLEPVLGLKV RSQSGELVPL
SEVVTVVDSS REHSIHHKNL LPVVYVQGDL AGGLDSPLYG MFDMFFGLRD TPMVHGEPLE
QRFISQPGDP YNYSLKWDGE WQVTYETFRD MGIAYGVGLI LIYLLIVAQF RSYMVPLVIM
APIPLTVIGV MPGHALVDAF FMDAKFTATS MIGMIALAGI IVRNSILLVD FINEELRRGV
DTIEAVVHAG AVRAKPIVLT GLAAMVGAGF ILDDPIFSGL AISLIFGVFV STVLTLVIIP
VLYYLYVRNR VDQIREQEA
//
